Loren J. Field, PhD
Distinguished Professor
Professor of Medicine
Professor of Anatomy, Cell Biology & Physiology
Professor of Pediatrics
Professor of Medicine, Physiology and Biophysics
Bio
Molecular biologist, Loren Field, PhD, is a professor of medicine, of physiology and biophysics and of pediatrics. He received his PhD at State University of New York at Buffalo and completed his postdoctoral fellowship at Foswell Park Memorial Institute, Buffalo, New York. Prior to his affiliation with Indiana University, Dr. Field was a staff investigator at the Cold Spring Harbor Laboratory, Cold Spring Harbor, New York.
Dr. Field and his IU colleagues were the first to show that relatively simple genetic modifications can induce mammalian heart cells to regenerate. His current research is focused on identify genes and molecules that promote heart muscle regeneration by coaxing healthy cells to proliferate. The success of this research would offer the potential for seriously ill patients whose tissue has been damaged by heart attack to "re-grow" their own hearts.
Year | Degree | Institution |
---|---|---|
2000 | Postdoctoral Training | Roswell Park Memorial Institute, Buffalo, New York |
1982 | PhD | State University of New York at Buffalo |
1980 | MS | State University of New York at Buffalo |
1978 | BA | State University of New York at Oswego |
Myocardial regeneration, cardiomyocyte cell cycle, cardiac grafts
Reuter SP; Soonpaa MH; Field D; Simpson E; Rubart-von der Lohe M; Lee HK; Sridhar A; Ware SM; Green N; Li X; Ofner S; Marchuk DA; Wollert KC; Field LJ; Circulation 2022 Nov 16
Reboll MR; Klede S; Taft MH; Cai CL; Field LJ; Lavine KJ; Koenig AL; Fleischauer J; Meyer J; Schambach A; Niessen HW; Kosanke M; van den Heuvel J; Pich A; Bauersachs J; Wu X; Zheng L; Wang Y; Korf-Klingebiel M; Polten F; Wollert KC; Science (New York, N.Y.) 2022 Jun 16
Tarasov KV; Chakir K; Riordon DR; Lyashkov AE; Ahmet I; Perino MG; Silvester AJ; Zhang J; Wang M; Lukyanenko YO; Qu JH; Barrera MC; Juhaszova M; Tarasova YS; Ziman B; Telljohann R; Kumar V; Ranek M; Lammons J; Bychkov R; de Cabo R; Jun S; Keceli G; Gupta A; Yang D; Aon MA; Adamo L; Morrell CH; Otu W; Carroll C; Chambers S; Paolocci N; Huynh T; Pacak K; Weiss R; Field L; Sollott SJ; Lakatta EG; eLife 2022 Dec 14
Wollert KC; Field LJ; Basic research in cardiology 2021 Mar 19
Tsai WC; Guo S; Olaopa MA; Field LJ; Yang J; Shen C; Chang CP; Chen PS; Rubart M; Circulation 2020 Sep 15
Firulli BA; George RM; Harkin J; Toolan KP; Gao H; Liu Y; Zhang W; Field LJ; Liu Y; Shou W; Payne RM; Rubart-von der Lohe M; Firulli AB; Cardiovascular research 2020 Mar 1
Anger M; Scheufele F; Ramanujam D; Meyer K; Nakajima H; Field LJ; Engelhardt S; Sarikas A; PloS one 2020 Dec 22
Eghbali A; Dukes A; Toischer K; Hasenfuss G; Field LJ; Current cardiology reports 2019 Sep 16
Zhu W; Reuter S; Field LJ; Cardiovascular research 2019 Apr 15
Wang J; Shen T; Zhu W; Dou L; Gu H; Zhang L; Yang Z; Chen H; Zhou Q; Sánchez ER; Field LJ; Mayo LD; Xie Z; Xiao D; Lin X; Shou W; Yong W; 2018 Sep 27
González-Rosa JM; Sharpe M; Field D; Soonpaa MH; Field LJ; Burns CE; Burns CG; 2018 Feb 26
Soonpaa MH; Lafontant PJ; Reuter S; Scherschel JA; Srour EF; Zaruba MM; Rubart-von der Lohe M; Field LJ; 2018 Dec 18
Field LJ; Shou W; Markham L; 2018 Aug
Toischer K; Zhu W; Hünlich M; Mohamed BA; Khadjeh S; Reuter SP; Schäfer K; Ramanujam D; Engelhardt S; Field LJ; Hasenfuss G; The Journal of clinical investigation 2017 Oct 30
Tschen SI; Zeng C; Field L; Dhawan S; Bhushan A; Georgia S; Cell cycle (Georgetown, Tex.) 2017 Nov 3
Eschenhagen T; Bolli R; Braun T; Field LJ; Fleischmann BK; Frisén J; Giacca M; Hare JM; Houser S; Lee RT; Marbán E; Martin JF; Molkentin JD; Murry CE; Riley PR; Ruiz-Lozano P; Sadek HA; Sussman MA; Hill JA; Circulation 2017 Jul 6
Soonpaa MH; Zebrowski DC; Platt C; Rosenzweig A; Engel FB; Field LJ; Cell 2015 Nov 5
Yang T; Rubart M; Soonpaa MH; Didié M; Christalla P; Zimmermann WH; Field LJ; PloS one 2015 Jun 25
Zhu W; Zhang W; Shou W; Field LJ; Cardiovascular research 2014 May 8
Reuter S; Soonpaa MH; Firulli AB; Chang AN; Field LJ; PloS one 2014 Dec 29
Scheufele F; Wolf B; Kruse M; Hartmann T; Lempart J; Muehlich S; Pfeiffer AF; Field LJ; Charron MJ; Pan ZQ; Engelhardt S; Sarikas A; Cellular signalling 2013 Nov 9
Chen H; Zhang W; Sun X; Yoshimoto M; Chen Z; Zhu W; Liu J; Shen Y; Yong W; Li D; Zhang J; Lin Y; Li B; VanDusen NJ; Snider P; Schwartz RJ; Conway SJ; Field LJ; Yoder MC; Firulli AB; Carlesso N; Towbin JA; Shou W; Development (Cambridge, England) 2013 May
Didié M; Christalla P; Rubart M; Muppala V; Döker S; Unsöld B; El-Armouche A; Rau T; Eschenhagen T; Schwoerer AP; Ehmke H; Schumacher U; Fuchs S; Lange C; Becker A; Tao W; Scherschel JA; Soonpaa MH; Yang T; Lin Q; Zenke M; Han DW; Schöler HR; Rudolph C; Steinemann D; Schlegelberger B; Kattman S; Witty A; Keller G; Field LJ; Zimmermann WH; The Journal of clinical investigation 2013 Feb 22
Soonpaa MH; Rubart M; Field LJ; Biochimica et biophysica acta 2012 Nov 7
Choi EK; Chang PC; Lee YS; Lin SF; Zhu W; Maruyama M; Fishbein MC; Chen Z; Rubart-von der Lohe M; Field LJ; Chen PS; Circulation journal : official journal of the Japanese Circulation Society 2012 Mar 22
Tao W; Soonpaa MH; Field LJ; Chen PS; Firulli AB; Shou W; Rubart M; Pediatric cardiology 2012 Apr 6
Zhang W; Chen H; Wang Y; Yong W; Zhu W; Liu Y; Wagner GR; Payne RM; Field LJ; Xin H; Cai CL; Shou W; The Journal of biological chemistry 2011 Sep 2
Lafontant PJ; Burns AR; Grivas JA; Lesch MA; Lala TD; Reuter SP; Field LJ; Frounfelter TD; Anatomical record (Hoboken, N.J. : 2007) 2011 Nov 18
Maruyama M; Li BY; Chen H; Xu X; Song LS; Guatimosim S; Zhu W; Yong W; Zhang W; Bu G; Lin SF; Fishbein MC; Lederer WJ; Schild JH; Field LJ; Rubart M; Chen PS; Shou W; Circulation research 2011 Mar 3
Knöll R; Linke WA; Zou P; Miocic S; Kostin S; Buyandelger B; Ku CH; Neef S; Bug M; Schäfer K; Knöll G; Felkin LE; Wessels J; Toischer K; Hagn F; Kessler H; Didié M; Quentin T; Maier LS; Teucher N; Unsöld B; Schmidt A; Birks EJ; Gunkel S; Lang P; Granzier H; Zimmermann WH; Field LJ; Faulkner G; Dobbelstein M; Barton PJ; Sattler M; Wilmanns M; Chien KR; Circulation research 2011 Jul 28
Li D; Hallett MA; Zhu W; Rubart M; Liu Y; Yang Z; Chen H; Haneline LS; Chan RJ; Schwartz RJ; Field LJ; Atkinson SJ; Shou W; Development (Cambridge, England) 2011 Jan
Li D; Liu Y; Maruyama M; Zhu W; Chen H; Zhang W; Reuter S; Lin SF; Haneline LS; Field LJ; Chen PS; Shou W; Human molecular genetics 2011 Aug 31
Zaruba MM; Zhu W; Soonpaa MH; Reuter S; Franz WM; Field LJ; European heart journal 2011 Aug 17
Ang KL; Shenje LT; Reuter S; Soonpaa MH; Rubart M; Field LJ; Galiñanes M; American journal of physiology. Cell physiology 2010 Mar 24
Firulli AB; Firulli BA; Wang J; Rogers RH; Conway SJ; Pediatric cardiology 2010 Feb 14
Toischer K; Rokita AG; Unsöld B; Zhu W; Kararigas G; Sossalla S; Reuter SP; Becker A; Teucher N; Seidler T; Grebe C; Preuss L; Gupta SN; Schmidt K; Lehnart SE; Krüger M; Linke WA; Backs J; Regitz-Zagrosek V; Schäfer K; Field LJ; Maier LS; Hasenfuss G; Circulation 2010 Aug 23
Zaruba MM; Soonpaa M; Reuter S; Field LJ; Circulation 2010 Apr 26
Hassink RJ; Nakajima H; Nakajima HO; Doevendans PA; Field LJ; Heart (British Cardiac Society) 2009 May 11
Field LJ; Shou W; Caldwell RL; Pediatric cardiology 2009 Apr 2
Zhu W; Hassink RJ; Rubart M; Field LJ; Pediatric cardiology 2009 Apr 2
Sarikas A; Xu X; Field LJ; Pan ZQ; Cell cycle (Georgetown, Tex.) 2008 Oct 4
Chen Q; Chen H; Zheng D; Kuang C; Fang H; Zou B; Zhu W; Bu G; Jin T; Wang Z; Zhang X; Chen J; Field LJ; Rubart M; Shou W; Chen Y; The Journal of biological chemistry 2008 Oct 24
Zhu W; Shou W; Payne RM; Caldwell R; Field LJ; Pediatric research 2008 Nov
Xu X; Sarikas A; Dias-Santagata DC; Dolios G; Lafontant PJ; Tsai SC; Zhu W; Nakajima H; Nakajima HO; Field LJ; Wang R; Pan ZQ; Molecular cell 2008 May 23
Shen WH; Chen Z; Shi S; Chen H; Zhu W; Penner A; Bu G; Li W; Boyle DW; Rubart M; Field LJ; Abraham R; Liechty EA; Shou W; The Journal of biological chemistry 2008 Mar 7
Snider P; Hinton RB; Moreno-Rodriguez RA; Wang J; Rogers R; Lindsley A; Li F; Ingram DA; Menick D; Field L; Firulli AB; Molkentin JD; Markwald R; Conway SJ; Circulation research 2008 Feb 22
Zhu W; Soonpaa MH; Chen H; Shen W; Payne RM; Liechty EA; Caldwell RL; Shou W; Field LJ; Circulation 2008 Dec 22
Yang L; Soonpaa MH; Adler ED; Roepke TK; Kattman SJ; Kennedy M; Henckaerts E; Bonham K; Abbott GW; Linden RM; Field LJ; Keller GM; Nature 2008 Apr 23
Scherschel JA; Soonpaa MH; Srour EF; Field LJ; Rubart M; Molecular therapy : the journal of the American Society of Gene Therapy 2008 Apr 22
Shenje LT; Field LJ; Pritchard CA; Guerin CJ; Rubart M; Soonpaa MH; Ang KL; Galiñanes M; PloS one 2008 Apr 16
Rubart M; Field LJ; Nature biotechnology 2007 Sep
Dai W; Field LJ; Rubart M; Reuter S; Hale SL; Zweigerdt R; Graichen RE; Kay GL; Jyrala AJ; Colman A; Davidson BP; Pera M; Kloner RA; Journal of molecular and cellular cardiology 2007 Jul 14
Rubart M; Field LJ; Cells, tissues, organs 2007 Dec 20
Hassink RJ; Pasumarthi KB; Nakajima H; Rubart M; Soonpaa MH; de la Rivière AB; Doevendans PA; Field LJ; Cardiovascular research 2007 Dec 12
van Laake LW; Passier R; Monshouwer-Kloots J; Nederhoff MG; Ward-van Oostwaard D; Field LJ; van Echteld CJ; Doevendans PA; Mummery CL; Nature protocols 2007
Field LJ; Molecular therapy : the journal of the American Society of Gene Therapy 2006 Oct 27
Rubart M; Field LJ; Annals of the New York Academy of Sciences 2006 Oct
Chen H; Yong W; Ren S; Shen W; He Y; Cox KA; Zhu W; Li W; Soonpaa M; Payne RM; Franco D; Field LJ; Rosen V; Wang Y; Shou W; The Journal of biological chemistry 2006 Jun 23
Dowell JD; Tsai SC; Dias-Santagata DC; Nakajima H; Wang Z; Zhu W; Field LJ; Biochimica et biophysica acta 2006 Dec 15
Lafontant PJ; Field LJ; Novartis Foundation symposium 2006
Rubart M; Field LJ; Annual review of physiology 2006
Rubart M; Field LJ; Handbook of experimental pharmacology 2006
Nakajima H; Nakajima HO; Dembowsky K; Pasumarthi KB; Field LJ; Circulation research 2005 Nov 23
Murry CE; Field LJ; Menasché P; Circulation 2005 Nov 15
Schroeder M; Niebruegge S; Werner A; Willbold E; Burg M; Ruediger M; Field LJ; Lehmann J; Zweigerdt R; Biotechnology and bioengineering 2005 Dec 30
Rubart M; Soonpaa MH; Nakajima H; Field LJ; The Journal of clinical investigation 2004 Sep
Nakajima H; Nakajima HO; Tsai SC; Field LJ; Circulation research 2004 May 13
Field LJ; Annals of the New York Academy of Sciences 2004 May
Strom TB; Field LJ; Ruediger M; Journal of the American Society of Nephrology : JASN 2004 May
Murry CE; Soonpaa MH; Reinecke H; Nakajima H; Nakajima HO; Rubart M; Pasumarthi KB; Virag JI; Bartelmez SH; Poppa V; Bradford G; Dowell JD; Williams DA; Field LJ; Nature 2004 Mar 21
Pasumarthi KB; Nakajima H; Nakajima HO; Soonpaa MH; Field LJ; Circulation research 2004 Dec 2
Verheule S; Sato T; Everett T 4th; Engle SK; Otten D; Rubart-von der Lohe M; Nakajima HO; Nakajima H; Field LJ; Olgin JE; Circulation research 2004 Apr 29
Hassink RJ; Dowell JD; Brutel de la Rivière A; Doevendans PA; Field LJ; Trends in molecular medicine 2003 Oct
Rubart M; Pasumarthi KB; Nakajima H; Soonpaa MH; Nakajima HO; Field LJ; Circulation research 2003 May 1
Dowell JD; Rubart M; Pasumarthi KB; Soonpaa MH; Field LJ; Cardiovascular research 2003 May 1
Dowell JD; Field LJ; Pasumarthi KB; Heart failure reviews 2003 Jul
Rubart M; Wang E; Dunn KW; Field LJ; American journal of physiology. Cell physiology 2003 Feb 12
Zandstra PW; Bauwens C; Yin T; Liu Q; Schiller H; Zweigerdt R; Pasumarthi KB; Field LJ; Tissue engineering 2003 Aug
Strom TB; Field LJ; Ruediger M; Current opinion in immunology 2002 Oct
Pasumarthi KB; Field LJ; Circulation research 2002 May 31
Pasumarthi KB; Field LJ; Methods in molecular biology (Clifton, N.J.) 2002
Murry CE; Whitney ML; Laflamme MA; Reinecke H; Field LJ; Cold Spring Harbor symposia on quantitative biology 2002
Pasumarthi KB; Tsai SC; Field LJ; Circulation research 2001 May 25
Huh NE; Pasumarthi KB; Soonpaa MH; Jing S; Patton B; Field LJ; Journal of molecular and cellular cardiology 2001 Aug
Reinlib L; Field L; Circulation 2000 May 9
Pasumarthi KB; Nakajima H; Nakajima HO; Jing S; Field LJ; Circulation research 2000 May 26
Nakajima H; Nakajima HO; Salcher O; Dittiè AS; Dembowsky K; Jing S; Field LJ; Circulation research 2000 Mar 17
Nakajima H; Nakajima HO; Soonpaa MH; Jing S; Field LJ; Oncogene 2000 Jan 6
Tsai SC; Pasumarthi KB; Pajak L; Franklin M; Patton B; Wang H; Henzel WJ; Stults JT; Field LJ; The Journal of biological chemistry 2000 Feb 4
Neumann J; Boknik P; DePaoli-Roach AA; Field LJ; Rockman HA; Kobayashi YM; Kelley JS; Jones LR; Journal of molecular and cellular cardiology 1998 Oct
Field LJ; Journal of cardiovascular electrophysiology 1998 Jun
Soonpaa MH; Field LJ; Circulation research 1998 Jul 13
Pajak L; Jin F; Xiao GH; Soonpaa MH; Field LJ; Yeung RS; The American journal of physiology 1997 Sep
Soonpaa MH; Koh GY; Pajak L; Jing S; Wang H; Franklin MT; Kim KK; Field LJ; The Journal of clinical investigation 1997 Jun 1
Soonpaa MH; Field LJ; The American journal of physiology 1997 Jan
Sutton J; Costa R; Klug M; Field L; Xu D; Largaespada DA; Fletcher CF; Jenkins NA; Copeland NG; Klemsz M; Hromas R; The Journal of biological chemistry 1996 Sep 20
Kim KK; Daud AI; Wong SC; Pajak L; Tsai SC; Wang H; Henzel WJ; Field LJ; The Journal of biological chemistry 1996 Nov 15
Soonpaa MH; Kim KK; Pajak L; Franklin M; Field LJ; The American journal of physiology 1996 Nov
Klug MG; Soonpaa MH; Koh GY; Field LJ; The Journal of clinical investigation 1996 Jul 1
Koh GY; Soonpaa MH; Klug MG; Pride HP; Cooper BJ; Zipes DP; Field LJ; The Journal of clinical investigation 1995 Oct
Hassankhani A; Steinhelper ME; Soonpaa MH; Katz EB; Taylor DA; Andrade-Rozental A; Factor SM; Steinberg JJ; Field LJ; Federoff HJ; Developmental biology 1995 May
Soonpaa MH; Daud AI; Koh GY; Klug MG; Kim KK; Wang H; Field LJ; Annals of the New York Academy of Sciences 1995 Mar 27
Veress AT; Chong CK; Field LJ; Sonnenberg H; The American journal of physiology 1995 Jul
Koh GY; Kim SJ; Klug MG; Park K; Soonpaa MH; Field LJ; The Journal of clinical investigation 1995 Jan
McDonald KS; Field LJ; Parmacek MS; Soonpaa M; Leiden JM; Moss RL; The Journal of physiology 1995 Feb 15
Klug MG; Soonpaa MH; Field LJ; The American journal of physiology 1995 Dec
Kim KK; Soonpaa MH; Wang H; Field LJ; Genomics 1995 Aug 10
Koh GY; Soonpaa MH; Klug MG; Field LJ; Journal of interventional cardiology 1995 Aug
Kim KK; Pajak L; Wang H; Field LJ; Cellular & molecular biology research 1995
Kim KK; Soonpaa MH; Daud AI; Koh GY; Kim JS; Field LJ; The Journal of biological chemistry 1994 Sep 9
Sonnenberg H; Honrath U; Chong CK; Field LJ; Veress AT; Canadian journal of physiology and pharmacology 1994 Oct
Smith JP; Kasten-Jolly J; Field LJ; Thomas JM; Transplantation 1994 Aug 15
Soonpaa MH; Koh GY; Klug MG; Field LJ; Science (New York, N.Y.) 1994 Apr 1
Barbee RW; Perry BD; Ré RN; Murgo JP; Field LJ; Circulation research 1994 Apr
Soonpaa MH; Field LJ; The American journal of physiology 1994 Apr
Lichardus B; Veress AT; Field LJ; Sonnenberg H; Physiological research / Academia Scientiarum Bohemoslovaca 1994
Koh GY; Klug MG; Soonpaa MH; Field LJ; The Journal of clinical investigation 1993 Sep
Metzger JM; Parmacek MS; Barr E; Pasyk K; Lin WI; Cochrane KL; Field LJ; Leiden JM; Proceedings of the National Academy of Sciences of the United States of America 1993 Oct 1
Koh GY; Klug MG; Field LJ; Hypertension 1993 Oct
Daud AI; Lanson NA Jr; Claycomb WC; Field LJ; The American journal of physiology 1993 May
Koh GY; Soonpaa MH; Klug MG; Field LJ; The American journal of physiology 1993 May
Jones LR; Field LJ; The Journal of biological chemistry 1993 Jun 5
Klinger JR; Petit RD; Curtin LA; Warburton RR; Wrenn DS; Steinhelper ME; Field LJ; Hill NS; Journal of applied physiology (Bethesda, Md. : 1985) 1993 Jul
Kline RP; Sorota S; Dresdner KP; Steinhelper ME; Lanson NA Jr; Wit AL; Claycomb WC; Field LJ; Journal of cardiovascular electrophysiology 1993 Dec
Field LJ; Annual review of physiology 1993
Lanson NA Jr; Glembotski CC; Steinhelper ME; Field LJ; Claycomb WC; Circulation 1992 May
Katz EB; Steinhelper ME; Delcarpio JB; Daud AI; Claycomb WC; Field LJ; The American journal of physiology 1992 Jun
Steinhelper ME; Field LJ; Genomics 1992 Jan
Veress AT; Field LJ; Steinhelper ML; Sonnenberg H; Clinical and investigative medicine. Me´decine clinique et experimentale 1992 Dec
Rockman HA; Ross RS; Harris AN; Knowlton KU; Steinhelper ME; Field LJ; Ross J Jr; Chien KR; Proceedings of the National Academy of Sciences of the United States of America 1991 Sep 15
Field LJ; Veress AT; Steinhelper ME; Cochrane K; Sonnenberg H; The American journal of physiology 1991 Jan
Steinhelper ME; Cochrane KL; Field LJ; Annals of the New York Academy of Sciences 1991 Dec 27
Delcarpio JB; Lanson NA Jr; Field LJ; Claycomb WC; Circulation research 1991 Dec
Steinhelper ME; Cochrane KL; Field LJ; Hypertension 1990 Sep
Steinhelper ME; Lanson NA Jr; Dresdner KP; Delcarpio JB; Wit AL; Claycomb WC; Field LJ; The American journal of physiology 1990 Dec
Steinhelper ME; Field LJ; Toxicologic pathology 1990
Fabian JR; Field LJ; McGowan RA; Mullins JJ; Sigmund CD; Gross KW; The Journal of biological chemistry 1989 Oct 15
Field LJ; Science (New York, N.Y.) 1988 Feb 26
Lee M; Pietras DF; Nemeroff ME; Corstanje BJ; Field LJ; Bruenn JA; Journal of virology 1986 May
Field LJ; Gross KW; Proceedings of the National Academy of Sciences of the United States of America 1985 Sep
Field LJ; Philbrick WM; Howles PN; Dickinson DP; McGowan RA; Gross KW; Molecular and cellular biology 1984 Nov
Field LJ; Bruenn JA; Chang TH; Pinhasi O; Koltin Y; Nucleic acids research 1983 May 11
Bobek LA; Bruenn JA; Field LJ; Gross KW; Gene 1982 Sep
Field LJ; Bobek LA; Brennan VE; Reilly JD; Bruenn JA; Cell 1982 Nov
Cardiac tumorigenesis, tuberous sclerosis, heart failure, heart repair, myocyte regeneration
Desc: Bicentennial Medal
Scope: University
Date: 2020-07-14
Desc: Distinguished Professor
Scope: University
Date: 2020-07-14
Desc: Glenn W. Irwin Research Scholar Award
Scope: University
Date: 2015-04-19