Sharon M. Moe, MD
Associate Dean for Clinical and Translational Research
Co-Director of Clinical and Translational Sciences Institute
Distinguished Professor
Stuart A. Kleit Professor of Nephrology
Professor of Medicine
Adjunct Professor of Anatomy, Cell Biology & Physiology
Division Chief
Adjunct Professor for Anatomy and Cell Biology
Bio
Sharon M. Moe, MD, is the Associate Dean for Clinical and Translational Research, and the Co-Director for the Indiana Clinical Translational Sciences Institute. She is also Director of the Division of Nephrology and Stuart A. Kleit Professor of Medicine for the Indiana University School of Medicine. She has been a faculty member at Indiana University since 1992, and in 2019 was named Distinguished Professor at IU. Dr. Moe is the principal investigator for several ongoing basic and clinical research studies in the field of Chronic Kidney Disease -Mineral Bone Disorder (CKD-MBD), including studies on vascular calcification, mineral metabolism and bone metabolism in kidney disease. Her research has been funded by the NIH and Veterans Affairs for over 20 years, in addition to funding from foundations and pharmaceutical companies. She has authored over 200 scientific manuscripts, teaching manuscripts and textbook chapters and has mentored over 25 pre/post docs and clinical fellows on NIH awards. Dr. Moe served on the National Kidney Foundation’s Bone and Mineral metabolism K/DOQI clinical practice guidelines in 2003, was co-chair of the international KDIGO Mineral and Bone guidelines released in 2009, and a member of the 2017 update committee. She has serves on numerous ad hoc NIH study sections, and was recently named as a standing member to the AMSC study section. Key Honors include election to the American Society for Clinical Research in 2005; the National Kidney Foundation in Gareb Eknoyan Award for exceptional contributions to key initiatives of the such as the Kidney Disease Outcomes Quality Initiative (KDOQI) in 2009; Councilor to the AHA Kidney Council (2002-2004), Councilor for the International Society of Nephrology (2005-2007), Councilor for the American Society of Nephrology from 2008- 2015; President of the American Society of Nephrology from 2013-2014, and election to the American Association of Physicians (AAP) in 2017.
Year | Degree | Institution |
---|---|---|
1992 | Postdoctoral Training | Department of Medicine, Section of Nephrology, University of Chicago, Chicago, IL |
1990 | Fellowship | Department of Medicine, Section of Nephrology, University of Chicago, Chicago, IL |
1989 | Residency | Loyola University Medical Center, Maywood, IL |
1986 | MD | University of Illinois |
1982 | BS | University of Illinois |
My research investigates the relationship of kidney disease, vascular calcification, bone, and disorders of mineral metabolism known as CKD-Mineral Bone Disorder (CKD-MBD). Our research is funded by the NIH, Veterans Administration, Food and Drug Administration, and industry and utilizes in vivo, ex vivo and in vitro techniques to investigate the pathophysiology of arterial medial calcification and bone disease. We are using a naturally occurring rat model of CKD that spontaneously develops all manifestations of CKD-MBD to study 1) mechanisms by which matrix vesicles propagate arterial calcification, 2) how oxidative stress alters vasculature, 3) the role of advanced glycation end product cross linking of bone collagen predisposes to fracture, 4) mechanisms of sudden cardiac death, 5) how impaired muscle function occurs with progressive CKD, and 6) micro RNA as biomarkers. We also have active investigator initiated clinical trials studying the natural progression of frailty and muscle weakness in patients as they start on dialysis, novel phosphate binders and the effect on phosphate balance, how nutrition can be enhanced in patients on dialysis, and the use of pioglitazone as a treatment for ADPKD.
Avin KG; Allen MR; Chen NX; Srinivasan S; O'Neill KD; Troutman AD; Mast G; Swallow EA; Brown MB; Wallace JM; Zimmers TA; Warden SJ; Moe SM; Journal of the American Society of Nephrology : JASN 2019 Sep 9
Jawed A; Moe SM; Moorthi RN; Torke AM; Eadon MT; American journal of nephrology 2019 Nov 19
Vorland CJ; Biruete A; Lachcik PJ; Srinivasan S; Chen NX; Moe SM; Hill Gallant KM; Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2019 Nov 15
Aref MW; Swallow EA; Metzger CE; Chen N; Moe SM; Allen MR; Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 2019 May 8
McNerny EMB; Buening DT; Aref MW; Chen NX; Moe SM; Allen MR; Bone 2019 May 3
Vorland CJ; Lachcik PJ; Swallow EA; Metzger CE; Allen MR; Chen NX; Moe SM; Hill Gallant KM; Scientific reports 2019 May 28
Biruete A; Hill Gallant KM; Lindemann SR; Wiese GN; Chen NX; Moe SM; Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation 2019 Mar 4
Fitzgerald C; Wiese G; Moorthi RN; Moe SM; Hill Gallant K; Running CA; Chemical senses 2019 Mar 11
Swallow EA; Aref MW; Metzger CE; Sacks S; Lehmkuhler DR; Chen N; Hammond MA; Territo PR; Nickolas TL; Moe SM; Allen MR; Bone 2019 Jul 9
Schwantes-An TH; Liu S; Stedman M; Decker BS; Wetherill L; Edenberg HJ; Vatta M; Foroud TM; Chertow GM; Moe SM; American journal of nephrology 2019 Jan 22
Clinkenbeard EL; Noonan ML; Thomas JC; Ni P; Hum JM; Aref M; Swallow EA; Moe SM; Allen MR; White KE; JCI insight 2019 Feb 21
Schwaderer AL; Raina R; Khare A; Safadi F; Moe SM; Kusumi K; Frontiers in pediatrics 2019 Feb 12
Chen NX; Srinivasan S; O'Neill K; Nickolas TL; Wallace JM; Allen MR; Metzger CE; Creecy A; Avin KG; Moe SM; Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2019 Dec 30
Warden SJ; Kemp AC; Liu Z; Moe SM; Gait & posture 2019 Aug 28
Wolf M; Block GA; Chertow GM; Cooper K; Fouqueray B; Moe SM; Sun Y; Tomlin H; Vervloet M; Oberbauer R; Clinical kidney journal 2019 Apr 26
Vorland CJ; Lachcik PJ; Aromeh LO; Moe SM; Chen NX; Hill Gallant KM; PloS one 2018 Nov 19
Chen NX; O'Neill KD; Moe SM; Kidney international 2017 Oct 9
Moe SM; Wetherill L; Decker BS; Lai D; Abdalla S; Long J; Vatta M; Foroud TM; Chertow GM; Clinical journal of the American Society of Nephrology : CJASN 2017 Jun 19
Moe SM; Current osteoporosis reports 2017 Jun
Wish JB; Moe SM; Journal of the American Society of Nephrology : JASN 2017 Jul 21
Ketteler M; Block GA; Evenepoel P; Fukagawa M; Herzog CA; McCann L; Moe SM; Shroff R; Tonelli MA; Toussaint ND; Vervloet MG; Leonard MB; Kidney international 2017 Jul
Block GA; Bushinsky DA; Cunningham J; Drueke TB; Ketteler M; Kewalramani R; Martin KJ; Mix TC; Moe SM; Patel UD; Silver J; Spiegel DM; Sterling L; Walsh L; Chertow GM; JAMA 2017 Jan 10
Block GA; Bushinsky DA; Cheng S; Cunningham J; Dehmel B; Drueke TB; Ketteler M; Kewalramani R; Martin KJ; Moe SM; Patel UD; Silver J; Sun Y; Wang H; Chertow GM; JAMA 2017 Jan 10
Moe SM; Comprehensive Physiology 2016 Sep 15
Moe SM; Nickolas TL; Clinical journal of the American Society of Nephrology : CJASN 2016 Oct 24
Rodenbeck SD; Zarse CA; McKenney-Drake ML; Bruning RS; Sturek M; Chen NX; Moe SM; Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2016 Aug 9
Avin KG; Chen NX; Organ JM; Zarse C; O'Neill K; Conway RG; Konrad RJ; Bacallao RL; Allen MR; Moe SM; PloS one 2016 Aug 3
Moe SM; Bone 2016 Aug 27
Organ JM; Srisuwananukorn A; Price P; Joll JE; Biro KC; Rupert JE; Chen NX; Avin KG; Moe SM; Allen MR; Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2015 Oct 5
Newman CL; Creecy A; Granke M; Nyman JS; Tian N; Hammond MA; Wallace JM; Brown DM; Chen N; Moe SM; Allen MR; Kidney international 2015 Oct 21
Pun PH; Abdalla S; Block GA; Chertow GM; Correa-Rotter R; Dehmel B; Drüeke TB; Floege J; Goodman WG; Herzog CA; London GM; Mahaffey KW; Moe SM; Parfrey PS; Wheeler DC; Middleton JP; Hemodialysis international. International Symposium on Home Hemodialysis 2015 Nov 13
Moe SM; Chen NX; Newman CL; Organ JM; Kneissel M; Kramer I; Gattone VH 2nd; Allen MR; Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2015 Mar
Moe SM; Journal of the American Society of Nephrology : JASN 2015 Jan 29
Moorthi RN; Armstrong CL; Janda K; Ponsler-Sipes K; Asplin JR; Moe SM; American journal of nephrology 2015 Jan 20
Moorthi RN; Fadel W; Eckert GJ; Ponsler-Sipes K; Moe SM; Lin C; Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 2015 Feb 21
Parfrey PS; Drüeke TB; Block GA; Correa-Rotter R; Floege J; Herzog CA; London GM; Mahaffey KW; Moe SM; Wheeler DC; Kubo Y; Dehmel B; Goodman WG; Chertow GM; for the Evaluation of Cinacalcet HCl Therapy to Lower Cardiovascular Events (EVOLVE) Trial Investigators; Clinical journal of the American Society of Nephrology : CJASN 2015 Feb 20
Zhao Y; Chen NX; Shirazi JT; Shen C; Lin SF; Fishbein MC; Moe SM; Chen PS; Heart rhythm : the official journal of the Heart Rhythm Society 2015 Dec 29
Wheeler DC; London GM; Parfrey PS; Block GA; Correa-Rotter R; Dehmel B; Drüeke TB; Floege J; Kubo Y; Mahaffey KW; Goodman WG; Moe SM; Trotman ML; Abdalla S; Chertow GM; Herzog CA; EValuation Of Cinacalcet HCl Therapy to Lower CardioVascular Events (EVOLVE) Trial Investigators; Journal of the American Heart Association 2014 Nov 17
Hsueh CH; Chen NX; Lin SF; Chen PS; Gattone VH 2nd; Allen MR; Fishbein MC; Moe SM; Journal of the American Society of Nephrology : JASN 2014 May 22
Chen NX; O'Neill K; Akl NK; Moe SM; Biochemical and biophysical research communications 2014 May 10
Newman CL; Moe SM; Chen NX; Hammond MA; Wallace JM; Nyman JS; Allen MR; PloS one 2014 Jun 9
Reilly AM; Gray AK; Moe SM; Ichikawa S; Bone 2014 Jul 4
Allen MR; Newman CL; Chen N; Granke M; Nyman JS; Moe SM; Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 2014 Dec 3
Moe SM; Abdalla S; Chertow GM; Parfrey PS; Block GA; Correa-Rotter R; Floege J; Herzog CA; London GM; Mahaffey KW; Wheeler DC; Dehmel B; Goodman WG; Drüeke TB; for the Evaluation of Cinacalcet HCl Therapy to Lower Cardiovascular Events (EVOLVE) Trial Investigators; Journal of the American Society of Nephrology : JASN 2014 Dec 11
Moe SM; Chen NX; Newman CL; Gattone VH 2nd; Organ JM; Chen X; Allen MR; Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2014 Apr
Allen MR; Chen NX; Gattone VH 2nd; Moe SM; American journal of nephrology 2013 Nov 22
Moe SM; Thadhani R; Current opinion in nephrology and hypertension 2013 Nov
Chen NX; Kiattisunthorn K; O'Neill KD; Chen X; Moorthi RN; Gattone VH 2nd; Allen MR; Moe SM; PloS one 2013 May 22
Moorthi RN; Moe SM; Kidney international 2013 Jun 26
Chen NX; O'Neill K; Chen X; Kiattisunthorn K; Gattone VH; Moe SM; American journal of nephrology 2013 Feb 28
Decker BS; O'Neill KD; Chambers MA; Slaven JE; Yu Z; Jones DR; Moe SM; Clinical pharmacology : advances and applications 2013 Dec 10
Gupta SK; Shen C; Moe SM; Kamendulis LM; Goldman M; Dubé MP; PloS one 2012 Sep 20
Chen NX; Moe SM; Current hypertension reports 2012 Jun
Decker BS; Mohamed AN; Chambers M; Kraus MA; Moe SM; Sowinski KM; American journal of nephrology 2012 Jul 18
Hill KM; Martin BR; Wastney ME; McCabe GP; Moe SM; Weaver CM; Peacock M; Kidney international 2012 Dec 19
Allen MR; Chen NX; Gattone VH 2nd; Chen X; Carr AJ; LeBlanc P; Brown D; Moe SM; Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 2012 Aug 21
Moorthi RN; Moe SM; American journal of kidney diseases : the official journal of the National Kidney Foundation 2011 Oct 21
Moe SM; Radcliffe JS; White KE; Gattone VH 2nd; Seifert MF; Chen X; Aldridge B; Chen NX; Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2011 Nov
Chen NX; Moe SM; Eggleston-Gulyas T; Chen X; Hoffmeyer WD; Bacallao RL; Herbert BS; Gattone VH 2nd; Kidney international 2011 Jun 1
Noureddine L; Landis M; Patel N; Moe SM; Clinical nephrology 2011 Jun
Chen NX; O'Neill KD; Chen X; Kiattisunthorn K; Gattone VH; Moe SM; American journal of nephrology 2011 Jul 23
Moorthi RN; Kandula P; Moe SM; Current opinion in nephrology and hypertension 2011 Jul
Moe SM; Seminars in dialysis 2010 Sep
Decker BS; Kays MB; Chambers M; Kraus MA; Moe SM; Sowinski KM; Clinical journal of the American Society of Nephrology : CJASN 2010 Jul 8
Chen NX; Chen X; O'Neill KD; Atkinson SJ; Moe SM; American journal of physiology. Renal physiology 2010 Jul 7
Moe SM; Saifullah A; LaClair RE; Usman SA; Yu Z; Clinical journal of the American Society of Nephrology : CJASN 2010 Jan 7
Moe SM; Zidehsarai MP; Chambers MA; Jackman LA; Radcliffe JS; Trevino LL; Donahue SE; Asplin JR; Clinical journal of the American Society of Nephrology : CJASN 2010 Dec 23
Noureddine LA; Usman SA; Yu Z; Moorthi RN; Moe SM; American journal of nephrology 2010 Aug 16
Gattone VH 2nd; Chen NX; Sinders RM; Seifert MF; Duan D; Martin D; Henley C; Moe SM; Journal of the American Society of Nephrology : JASN 2009 May 7
Moe SM; Seifert MF; Chen NX; Sinders RM; Chen X; Duan D; Henley C; Martin D; Gattone VH 2nd; Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2009 Mar 3
Chong CK; Muzoora M; Eckert GJ; Kamalesh M; Moe SM; Hemodialysis international. International Symposium on Home Hemodialysis 2009 Jun 22
Zidehsarai MP; Moe SM; Nephrology (Carlton, Vic.) 2009 Jun
Chen NX; Kircelli F; O'Neill KD; Chen X; Moe SM; Kidney international 2009 Dec 16
Moe SM; Chen NX; Seifert MF; Sinders RM; Duan D; Chen X; Liang Y; Radcliff JS; White KE; Gattone VH 2nd; Kidney international 2008 Sep 17
Moe SM; Drüeke T; Clinical journal of the American Society of Nephrology : CJASN 2008 Nov
Chen NX; O'Neill KD; Chen X; Moe SM; Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2008 Nov
LaClair R; O'Neal K; Ofner S; Sosa MJ; Labarrere CA; Moe SM; American journal of nephrology 2008 May 28
Moe SM; Primary care 2008 Jun
Moe SM; Pampalone AJ; Ofner S; Rosenman M; Teal E; Hui SL; American journal of kidney diseases : the official journal of the National Kidney Foundation 2008 Apr 28
Saifullah A; Watkins BA; Saha C; Li Y; Moe SM; Friedman AN; Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2007 Jul 10
Moe SM; Drüeke T; Lameire N; Eknoyan G; Advances in chronic kidney disease 2007 Jan
Moe SM; Chen NX; Journal of the American Society of Nephrology : JASN 2007 Dec 19
Moe SM; Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2007 Dec
Chen NX; Duan D; O'Neill KD; Moe SM; Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2006 Sep 27
Chen NX; O'Neill KD; Chen X; Duan D; Wang E; Sturek MS; Edwards JM; Moe SM; American journal of physiology. Renal physiology 2006 Sep 12
Chen NX; Moe SM; Journal of investigative medicine : the official publication of the American Federation for Clinical Research 2006 Nov
Moe SM; Kidney international 2006 Nov
Friedman AN; Moe SM; Perkins SM; Li Y; Watkins BA; American journal of kidney diseases : the official journal of the National Kidney Foundation 2006 Jun
Chen NX; Duan D; O'Neill KD; Wolisi GO; Koczman JJ; Laclair R; Moe SM; Kidney international 2006 Jul 12
Moe SM; European journal of clinical investigation 2006 Aug
Moe SM; Chertow GM; Clinical journal of the American Society of Nephrology : CJASN 2006 Apr 26
LaClair RE; Hellman RN; Karp SL; Kraus M; Ofner S; Li Q; Graves KL; Moe SM; American journal of kidney diseases : the official journal of the National Kidney Foundation 2005 Jun
Moe SM; Reslerova M; Ketteler M; O'neill K; Duan D; Koczman J; Westenfeld R; Jahnen-Dechent W; Chen NX; Kidney international 2005 Jun
Moe SM; Cunningham J; Bommer J; Adler S; Rosansky SJ; Urena-Torres P; Albizem MB; Guo MD; Zani VJ; Goodman WG; Sprague SM; Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2005 Jul 19
Wolisi GO; Moe SM; Seminars in dialysis 2005 Jul
Moe SM; Chen NX; Clinical calcium 2002 Oct
Fiddian-Green RG; Silen W; The American journal of physiology 1975 Dec
My clinical interests focus on the prevention and treatment of kidney stones using diet and medications. In addition I specialize in the treatment of bone disease in patients with kidney disease, and disorders of magnesium and calcium.
Desc: Trustee Teaching Award
Scope: University
Date: 2004-05-01
Desc: Bicentennial Medal
Scope: University
Date: 1905-07-14
Desc: Distinguished Professor
Scope: University
Date: 1905-07-13
Desc: Elected Member
Scope: National
Date: 1905-07-11
Desc: Gareb Eknoyan Award, exceptional contributions to key initiatives
Scope: National
Date: 1905-07-03
Desc: Elected Member
Scope: National
Date: 1905-06-29
Desc: Councilor to Kidney Council
Scope: National
Date:
Desc: Councilor
Scope: National
Date:
Desc: President
Scope: National
Date:
Desc: Councilor
Scope: International
Date: