G. David D. Roodman, MD, PhD
Distinguished Professor Emeritus
Professor Emeritus of Medicine
Professor Emeritus of Biochemistry & Molecular Biology
- Phone
- (317) 274-0843
- Address
-
Joseph E. Walther Hall, Room C312
980 W. Walnut St.
Indianapolis , IN 46202 - PubMed:
Year | Degree | Institution |
---|---|---|
1975 | PhD | University of Kentucky |
1973 | MD | University of Kentucky |
1969 | AB | Johns Hopkins University |
1 | Fellowship | University of Minnesota |
1 | Residency | University of Minnesota |
Research focuses on osteoclasts and osteoblast activity in both normal and pathological states including Paget’s disease and Multiple Myeloma.
Increased S1P expression in osteoclasts enhances bone formation in an animal model of Paget's disease.
Nagata Y; Miyagawa K; Ohata Y; Petrusca DN; Pagnotti GM; Mohammad KS; Guise TA; Windle JJ; David Roodman G; Kurihara N; Journal of cellular biochemistry 2020 Oct 27
Nagata Y; Miyagawa K; Ohata Y; Petrusca DN; Pagnotti GM; Mohammad KS; Guise TA; Windle JJ; David Roodman G; Kurihara N; Journal of cellular biochemistry 2020 Oct 27
Osteocyte Vegf-a contributes to myeloma-associated angiogenesis and is regulated by Fgf23.
Mulcrone PL; Edwards SKE; Petrusca DN; Haneline LS; Delgado-Calle J; Roodman GD; Scientific reports 2020 Oct 14
Mulcrone PL; Edwards SKE; Petrusca DN; Haneline LS; Delgado-Calle J; Roodman GD; Scientific reports 2020 Oct 14
Growth factor independence 1 expression in myeloma cells enhances their growth, survival, and osteoclastogenesis.
Petrusca DN; Toscani D; Wang FM; Park C; Crean CD; Anderson JL; Marino S; Mohammad KS; Zhou D; Silbermann R; Sun Q; Kurihara N; Galson DL; Giuliani N; Roodman GD; Journal of hematology & oncology 2018 Oct 4
Petrusca DN; Toscani D; Wang FM; Park C; Crean CD; Anderson JL; Marino S; Mohammad KS; Zhou D; Silbermann R; Sun Q; Kurihara N; Galson DL; Giuliani N; Roodman GD; Journal of hematology & oncology 2018 Oct 4
A cost-effectiveness analysis of denosumab for the prevention of skeletal-related events in patients with multiple myeloma in the United States of America.
Raje N; Roodman GD; Willenbacher W; Shimizu K; García-Sanz R; Terpos E; Kennedy L; Sabatelli L; Intorcia M; Hechmati G; 2018 Mar 5
Raje N; Roodman GD; Willenbacher W; Shimizu K; García-Sanz R; Terpos E; Kennedy L; Sabatelli L; Intorcia M; Hechmati G; 2018 Mar 5
Role of Bone-Modifying Agents in Multiple Myeloma: American Society of Clinical Oncology Clinical Practice Guideline Update.
Anderson K; Ismaila N; Flynn PJ; Halabi S; Jagannath S; Ogaily MS; Omel J; Raje N; Roodman GD; Yee GC; Kyle RA; 2018 Jan 17
Anderson K; Ismaila N; Flynn PJ; Halabi S; Jagannath S; Ogaily MS; Omel J; Raje N; Roodman GD; Yee GC; Kyle RA; 2018 Jan 17
Denosumab versus zoledronic acid in bone disease treatment of newly diagnosed multiple myeloma: an international, double-blind, double-dummy, randomised, controlled, phase 3 study.
Raje N; Terpos E; Willenbacher W; Shimizu K; García-Sanz R; Durie B; Legiec W; Krejcí M; Laribi K; Zhu L; Cheng P; Warner D; Roodman GD; 2018 Feb 9
Raje N; Terpos E; Willenbacher W; Shimizu K; García-Sanz R; Durie B; Legiec W; Krejcí M; Laribi K; Zhu L; Cheng P; Warner D; Roodman GD; 2018 Feb 9
Multiple Myeloma and Bone: The Fatal Interaction.
Marino S; Roodman GD; 2018 Aug 1
Marino S; Roodman GD; 2018 Aug 1
Genetic deletion of Sost or pharmacological inhibition of sclerostin prevent multiple myeloma-induced bone disease without affecting tumor growth.
Delgado-Calle J; Anderson J; Cregor MD; Condon KW; Kuhstoss SA; Plotkin LI; Bellido T; Roodman GD; 2017 May 22
Delgado-Calle J; Anderson J; Cregor MD; Condon KW; Kuhstoss SA; Plotkin LI; Bellido T; Roodman GD; 2017 May 22
Management of Aromatase Inhibitor-Associated Bone Loss (AIBL) in postmenopausal women with hormone sensitive breast cancer: Joint position statement of the IOF, CABS, ECTS, IEG, ESCEO IMS, and SIOG.
Hadji P; Aapro MS; Body JJ; Gnant M; Brandi ML; Reginster JY; Zillikens MC; Glüer CC; de Villiers T; Baber R; Roodman GD; Cooper C; Langdahl B; Palacios S; Kanis J; Al-Daghri N; Nogues X; Eriksen EF; Kurth A; Rizzoli R; Coleman RE; 2017 Mar 23
Hadji P; Aapro MS; Body JJ; Gnant M; Brandi ML; Reginster JY; Zillikens MC; Glüer CC; de Villiers T; Baber R; Roodman GD; Cooper C; Langdahl B; Palacios S; Kanis J; Al-Daghri N; Nogues X; Eriksen EF; Kurth A; Rizzoli R; Coleman RE; 2017 Mar 23
Bone Pain Induced by Multiple Myeloma Is Reduced by Targeting V-ATPase and ASIC3.
Hiasa M; Okui T; Allette YM; Ripsch MS; Sun-Wada GH; Wakabayashi H; Roodman GD; White FA; Yoneda T; 2017 Mar 2
Hiasa M; Okui T; Allette YM; Ripsch MS; Sun-Wada GH; Wakabayashi H; Roodman GD; White FA; Yoneda T; 2017 Mar 2
EZH2 or HDAC1 Inhibition Reverses Multiple Myeloma-Induced Epigenetic Suppression of Osteoblast Differentiation.
Adamik J; Jin S; Sun Q; Zhang P; Weiss KR; Anderson JL; Silbermann R; Roodman GD; Galson DL; 2017 Jan 23
Adamik J; Jin S; Sun Q; Zhang P; Weiss KR; Anderson JL; Silbermann R; Roodman GD; Galson DL; 2017 Jan 23
NEK2 induces osteoclast differentiation and bone destruction via heparanase in multiple myeloma.
Hao M; Franqui-Machin R; Xu H; Shaughnessy J Jr; Barlogie B; Roodman D; Quelle DE; Janz S; Tomasson MH; Sanderson RD; Qiu L; Frech I; Tricot G; Zhan F; 2017 Apr 12
Hao M; Franqui-Machin R; Xu H; Shaughnessy J Jr; Barlogie B; Roodman D; Quelle DE; Janz S; Tomasson MH; Sanderson RD; Qiu L; Frech I; Tricot G; Zhan F; 2017 Apr 12
The Role of Percutaneous Vertebroplasty and Balloon Kyphoplasty for the Treatment of Vertebral Compression Fractures in Multiple Myleoma: New Consensus Statement from the International Myeloma Working Group
Roodman GD Leukemia 2017
Roodman GD Leukemia 2017
Role of magnetic resonance imaging in the management of patients with multiple myeloma: a consensus statement.
Dimopoulos MA; Hillengass J; Usmani S; Zamagni E; Lentzsch S; Davies FE; Raje N; Sezer O; Zweegman S; Shah J; Badros A; Shimizu K; Moreau P; Chim CS; Lahuerta JJ; Hou J; Jurczyszyn A; Goldschmidt H; Sonneveld P; Palumbo A; Ludwig H; Cavo M; Barlogie B; Anderson K; Roodman GD; Rajkumar SV; Durie BG; Terpos E; Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2015 Jan 20
Dimopoulos MA; Hillengass J; Usmani S; Zamagni E; Lentzsch S; Davies FE; Raje N; Sezer O; Zweegman S; Shah J; Badros A; Shimizu K; Moreau P; Chim CS; Lahuerta JJ; Hou J; Jurczyszyn A; Goldschmidt H; Sonneveld P; Palumbo A; Ludwig H; Cavo M; Barlogie B; Anderson K; Roodman GD; Rajkumar SV; Durie BG; Terpos E; Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2015 Jan 20
CCN1: a sticky issue in myeloma.
Roodman GD; Blood 2014 Sep 25
Roodman GD; Blood 2014 Sep 25
Autoreactivity to glucose regulated protein 78 links emphysema and osteoporosis in smokers.
Bon J; Kahloon R; Zhang Y; Xue J; Fuhrman CR; Tan J; Burger M; Kass DJ; Csizmadia E; Otterbein L; Chandra D; Bhargava A; Pilewski JM; Roodman GD; Sciurba FC; Duncan SR; PloS one 2014 Sep 12
Bon J; Kahloon R; Zhang Y; Xue J; Fuhrman CR; Tan J; Burger M; Kass DJ; Csizmadia E; Otterbein L; Chandra D; Bhargava A; Pilewski JM; Roodman GD; Sciurba FC; Duncan SR; PloS one 2014 Sep 12
Whole-body low-dose computed tomography and advanced imaging techniques for multiple myeloma bone disease.
Pianko MJ; Terpos E; Roodman GD; Divgi CR; Zweegman S; Hillengass J; Lentzsch S; Clinical cancer research : an official journal of the American Association for Cancer Research 2014 Oct 7
Pianko MJ; Terpos E; Roodman GD; Divgi CR; Zweegman S; Hillengass J; Lentzsch S; Clinical cancer research : an official journal of the American Association for Cancer Research 2014 Oct 7
Pathobiology of Paget's Disease of Bone.
Galson DL; Roodman GD; Journal of bone metabolism 2014 May 31
Galson DL; Roodman GD; Journal of bone metabolism 2014 May 31
Increased IL-6 expression in osteoclasts is necessary but not sufficient for the development of Paget's disease of bone.
Teramachi J; Zhou H; Subler MA; Kitagawa Y; Galson DL; Dempster DW; Windle JJ; Kurihara N; Roodman GD; Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2014 Jun
Teramachi J; Zhou H; Subler MA; Kitagawa Y; Galson DL; Dempster DW; Windle JJ; Kurihara N; Roodman GD; Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2014 Jun
Role of osteocytes in multiple myeloma bone disease.
Delgado-Calle J; Bellido T; Roodman GD; Current opinion in supportive and palliative care 2014 Dec
Delgado-Calle J; Bellido T; Roodman GD; Current opinion in supportive and palliative care 2014 Dec
Advances in supportive care for multiple myeloma.
Raje NS; Yee AJ; Roodman GD; Journal of the National Comprehensive Cancer Network : JNCCN 2014 Apr
Raje NS; Yee AJ; Roodman GD; Journal of the National Comprehensive Cancer Network : JNCCN 2014 Apr
Role of ATF7-TAF12 interactions in the vitamin D response hypersensitivity of osteoclast precursors in Paget's disease.
Teramachi J; Hiruma Y; Ishizuka S; Ishizuka H; Brown JP; Michou L; Cao H; Galson DL; Subler MA; Zhou H; Dempster DW; Windle JJ; Roodman GD; Kurihara N; Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2013 Jun
Teramachi J; Hiruma Y; Ishizuka S; Ishizuka H; Brown JP; Michou L; Cao H; Galson DL; Subler MA; Zhou H; Dempster DW; Windle JJ; Roodman GD; Kurihara N; Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2013 Jun
Genes associate with abnormal bone cell activity in bone metastasis.
Roodman GD; Cancer metastasis reviews 2012 Dec
Roodman GD; Cancer metastasis reviews 2012 Dec
Auditory stimulation alters the pattern of 2-deoxyglucose uptake in the inner ear.
Ryan AF; Goodwin P; Woolf NK; Sharp F; Brain research 1982 Feb 25
Ryan AF; Goodwin P; Woolf NK; Sharp F; Brain research 1982 Feb 25
[Electrophysiologic study of limbic-hypothalamic interrelationships].
Grachev II; Petrov IuA; Chernysheva MP; Nervnaia sistema 1980
Grachev II; Petrov IuA; Chernysheva MP; Nervnaia sistema 1980
American Board of Internal Medicine - Hematology
American Board of Internal Medicine - Internal Medicine
Paget’s disease and Multiple Myeloma
Org: Indiana University
Desc: Bicentennial Medal
Scope: University
Date: 1905-07-14
Desc: Bicentennial Medal
Scope: University
Date: 1905-07-14
Org: Indiana University
Desc: Distinguished Professor
Scope: University
Date: 1905-07-14
Desc: Distinguished Professor
Scope: University
Date: 1905-07-14
Org: American Association for the Advancement of Science
Desc: Fellow (Biological Sciences)
Scope: National
Date: 1905-07-06
Desc: Fellow (Biological Sciences)
Scope: National
Date: 1905-07-06
Org: The American Society for Clinical Investigation
Desc: Elected Member
Scope: National
Date: 1905-06-15
Desc: Elected Member
Scope: National
Date: 1905-06-15
Research Labs
Faculty research at IU School of Medicine is transforming health. Details about the medical research being conducted in faculty labs throughout IU School of Medicine are available in the Research section of this site.