51977-Warmke, Laura

Laura M. Warmke, MD

Assistant Professor of Clinical Pathology & Laboratory Medicine

Director of Bone and Soft Tissue Pathology Fellowship

Chair of Clinical Competency Committee

Editorial Board, Bone and Soft Tissue Pathology, PathologyOutlines.com

Address
IU Health Pathology Laboratory
350 W 11th Street, Rm 4086
Indianapolis, IN 46202
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Bio

Laura M. Warmke, M.D., is an Assistant Professor of Pathology and Laboratory Medicine and serves as the Director of the Bone & Soft Tissue Pathology Fellowship at the Indiana University School of Medicine.  A native of Virginia, Dr. Warmke completed medical school and training in anatomic and clinical pathology at Virginia Commonwealth University in her hometown of Richmond, VA.  She subsequently completed fellowships in both Selective Surgical Pathology and Bone & Soft Tissue Pathology at The University of Texas MD Anderson in Houston, TX.

Key Publications

Warmke LM, Folpe AL. Fusion-positive soft tissue tumors: A selective review. Semin Diagn Pathol. 2026 Mar 4:150997. doi: 10.1016/j.semdp.2026.150997. Epub ahead of print. PMID: 41807226

Warmke LM, Toklu A, Richardson SM, Collier CD, Wurtz LD, Ladd LM, Shrestha R, Conway DJ. TRAF7-Mutated Fibromyxoid Spindle Cell Tumor of Bone: An Osseous Case Expanding the Spectrum of TRAF7-Mutated Tumors With Over 20 Years Clinical Follow-Up. Genes Chromosomes Cancer. 2026 Mar;65(3):e70118. doi: 10.1002/gcc.70118. PMID: 41811066

Warmke LM, Ameline B, Fritchie KJ, Dehner CA, Agaimy A, Din NU, Miettinen MM, Dermawan JK, Gross JM, Thangaiah JJ, Chrisinger JSA, Suster DI, Perret R, Le Loarer F, Charville GW, Buehler D, Yeung MCF, Smith BF, Baumhoer D, Davis JL. YAP1::KMT2A-rearranged sarcomas harbor a unique methylation profile and are distinct from sclerosing epithelioid fibrosarcoma and low-grade fibromyxoid sarcoma. Virchows Arch. 2025 Mar;486(3):457-477. doi: 10.1007/s00428-024-03995-2. Epub 2024 Dec 6. PMID: 39641785

Warmke LM, Strike SA, Fayad LM, Ahlawat S, Liu YJ, Mata DA, Rooper L, Baraban E, Zou YS, Gross JM. Undifferentiated Round Cell Sarcoma With CRTC1::SS18 Fusion: Expanding Clinicopathologic Features of a Rare Translocation Sarcoma With Prominent Desmoplastic Stroma. Mod Pathol. 2024 Sep;37(9):100555. doi: 10.1016/j.modpat.2024.100555. Epub 2024 Jul 6. PMID: 38972355

Warmke LM, Collier CD, Niziolek PJ, Davis JL, Zou YS, Michal M, Bell RC, Policarpio-Nicolas MLC, Cheng YW, Duckworth L, Dermawan JK, Fritchie KJ, Dehner CA. Novel CRTC1::MRTFB(MKL2) Gene Fusion Detected in Myxoid Mesenchymal Neoplasms With Myogenic Differentiation Involving Bone and Soft Tissues. Mod Pathol. 2024 Jul;37(7):100518. doi: 10.1016/j.modpat.2024.100518. Epub 2024 May 17. PMID: 38763420

Warmke LM, Yu W, Meis JM. Sclerosing Epithelioid Fibrosarcoma. Surg Pathol Clin. 2024 Mar;17(1):119-139. doi: 10.1016/j.path.2023.06.009. Epub 2023 Aug 5. PMID: 38278601.

Warmke LM, Mustafa A, Zou YS, Davis JL, Ulbright TM, Segura SE. Myxoid epithelioid smooth muscle tumor of the vulva: A distinct entity with MEF2D::NCOA2 gene fusion. Genes Chromosomes Cancer. 2024 Jan;63(1):e23209. doi: 10.1002/gcc.23209. Epub 2023 Oct 23. PMID: 37870842.

Warmke LM, Perret R, Ledoux P, Michot A, Italiano A, Zou YS, Matoso A, Argani P, Ulbright TM, Baumhoer D, Ameline B, Gross JM. EWSR1::WT1 Fusions in Neoplasms Other Than Conventional Desmoplastic Small Round Cell Tumor: Three Tumors Occurring Outside the Female Genital Tract. Mod Pathol. 2023 Dec 27;37(3):100418. doi: 10.1016/j.modpat.2023.100418. Epub ahead of print. PMID: 38158126.

Warmke LM, Collier CD, Davis JL. NR1D1::MAML1 epithelioid and spindle cell sarcoma mimicking pseudomyogenic hemangioendothelioma in core biopsy: A case report and review of the literature. Genes Chromosomes Cancer. 2023 Nov;62(11):655-662. doi: 10.1002/gcc.23186. Epub 2023 Jun 16. PMID: 37326138.

Warmke LM, Al-Ibraheemi A, Wang L, Parham D, Rudzinski ER, Stohr BA, Miles C, Habeeb O, Davis JL. FGFR1 gene fusions in a subset of pediatric mesenchymal tumors: Expanding the genetic spectrum of tumors sharing histologic overlap with infantile fibrosarcoma and "NTRK-rearranged" spindle cell neoplasms. Genes Chromosomes Cancer. 2023 Nov;62(11):641-647. doi: 10.1002/gcc.23179. Epub 2023 Jun 2. PMID: 37265193.

Warmke LM, Michal M, Martínek P, Agaimy A, Din NU, Perret R, Hostein I, Le Loarer F, Voltaggio L, Gross JM. "PRRX1-rearranged mesenchymal tumors": expanding the immunohistochemical profile and molecular spectrum of a recently described entity with the proposed revision of nomenclature. Virchows Arch. 2023 Aug;483(2):207-214. doi: 10.1007/s00428-023-03575-w. Epub 2023 Jun 20. PMID: 37338620.

Warmke LM, Wang WL, Baumhoer D, Andrei V, Ameline B, Baker ML, Kerr DA. TAF15::NR4A3 gene fusion identifies a morphologically distinct subset of extraskeletal myxoid chondrosarcoma mimicking myoepithelial tumors. Genes Chromosomes Cancer. 2023 Oct;62(10):581-588. doi: 10.1002/gcc.23144. Epub 2023 Apr 14. PMID: 37057757.

Warmke LM, Cheng L, Sperling RM, Sen JD, Ulbright TM. Atypical cartilage in type II germ cell tumors of the mediastinum show significantly different patterns of IDH1/2 mutations from conventional chondrosarcoma. Mod Pathol. 2022 Nov;35(11):1636-1643. doi: 10.1038/s41379-022-01106-7. Epub 2022 Jun 3. PMID: 35660795.

Warmke LM, Tinkham EG, Ingram DR, Lazar AJ, Panse G, Wang WL. INSM1 Expression in Angiosarcoma. Am J Clin Pathol. 2021 Mar 15;155(4):575-580. doi: 10.1093/ajcp/aqaa168. PMID: 33210141.

Warmke LM, Meis JM. Sclerosing Epithelioid Fibrosarcoma: A Distinct Sarcoma With Aggressive Features. Am J Surg Pathol. 2021 Mar 1;45(3):317-328. doi: 10.1097/PAS.0000000000001559. PMID: 32769431.

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