63227-Peng, Gang

Gang Peng, PhD

Assistant Professor of Medical & Molecular Genetics

Director of Bioinformatics Indiana Center for Musculoskeletal Health

Co-Director Collaborative Metabolome Core

Address
MS 502
MMGE
IN
Indianapolis, IN
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Bio


Dr. Peng is an Assistant Professor of Bioinformatics in the Department of Medical and Molecular Genetics at Indiana University School of Medicine (IUSM), Director of Bioinformatics at the Indiana Center for Musculoskeletal Health (ICMH), and Co-Director of the Collaborative Metabolome Core. He is princial investigator of Computational & Molecular Genetics Lab. Dr. Peng received his Ph.D degree mentored by Dr. Wenyi Wang from MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences. He finished his postdoctoral training under the supervision of Drs. Hongyu Zhao and Curt Scharfe in Yale School of Public Health and Yale School of Medicine.  He continued his research as a research faculty at Yale and joined IUSM in September 2022.

Key Publications

Brooks, S., Robins, M., Gao, H., Yu, X., Nho, K., Saykin, A., Liu, Y., & Peng, G. (2026). Comparison of nanopore sequencing, MethylationEPIC array, and EM-Seq for DNA methylation detection. Computational Biology and Chemistry, 124(Pt 2), 109204.

Kitase, Y., Ji, J., Bonewald, L. F., Prideaux, M., Roh, H. C., & Peng, G. (2026). High-resolution profiling of osteocyte transcriptomes via single-nucleus RNA sequencing. JBMR Plus, 10(5), ziag051.

Xiao, C.*, Peng, G.*, Conneely, K. N., Zhao, H., Felger, J. C., Wommack, E. C., Higgins, K. A., Shin, D. M., Saba, N. F., Bruner, D. W., & Miller, A. H. (2025). DNA methylation profiles of cancer-related fatigue associated with markers of inflammation and immunometabolism. Molecular Psychiatry, 30(1), 76-83. * authors contributed equally

Peng, G., Deosthale, P., Pianeta, R., Messersmith, H. M., & Plotkin, L. I. (2024). Sex dimorphic response to osteocyte miR21 deletion in murine calvaria bone as determined by RNAseq analysis. JBMR Plus, 8(6), ziae054.

Peng, G., Zhou, Q., Chai, H., Wen, J., Zhao, H., Taylor, H. S., Jiang, Y. H., & Li, P. (2023). Estimation on risk of spontaneous abortions by genomic disorders from a meta-analysis of microarray results on large case series of pregnancy losses. Molecular Genetics & Genomic Medicine, 11(8), e2181.

Peng, G., Xi, Y., Bellini, C., Pham, K., Zhuang, Z. W., Yan, Q., Jia, M., Wang, G., Lu, L., Tang, M. S., Zhao, H., & Wang, H. (2022). Nicotine dose-dependent epigenomic-wide DNA methylation changes in the mice with long-term electronic cigarette exposure. American Journal of Cancer Research, 12(8), 3679-3692.

Peng, G., Chai, H., Ji, W., Lu, Y., Wu, S., Zhao, H., Li, P., & Hu, Q. (2021). Correlating genomic copy number alterations with clinicopathologic findings in 75 cases of hepatocellular carcinoma. BMC Medical Genomics, 14(1), 150.

Peng, G., Tang, Y., Cowan, T. M., Enns, G. M., Zhao, H., & Scharfe, C. (2020). Reducing false-positive results in newborn screening using machine learning. International Journal of Neonatal Screening, 6(1), 16.

Peng, G., Shen, P., Gandotra, N., Le, A., Fung, E., Jelliffe-Pawlowski, L., Davis, R. W., Enns, G. M., Zhao, H., Cowan, T. M., & Scharfe, C. (2019). Combining newborn metabolic and DNA analysis for second-tier testing of methylmalonic acidemia. Genetics in Medicine, 21(4), 896-903.

Peng, G., Fan, Y., Palculict, T. B., Shen, P., Ruteshouser, E. C., Chi, A. K., Davis, R. W., Huff, V., Scharfe, C., & Wang, W. (2013). Rare variant detection using family-based sequencing analysis. Proceedings of the National Academy of Sciences of the United States of America, 110(10), 3985-90.

Full List of Publication

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