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Research

Accelerating the discovery of meaningful insights into practice-changing research and medicine.

At IU School of Medicine, we leverage real-world evidence (RWE) to understand how medical treatments and interventions perform in everyday clinical practice. Unlike traditional clinical trials, RWE studies analyze data collected from diverse sources like electronic health records, health surveys, clinical studies and patient registries, providing vital insights into patient outcomes and healthcare effectiveness in real-world settings.

Data accessed by IU School of Medicine students and researchers through the RWE DataLab is sourced from nationally deployed HIPAA-compliant electronic health record systems through a collective network of 37,000 community-based primary care and specialty care providers across all 50 states. The real-world data has been de-identified and certified by independent expert determination with 99.7% efficacy.

IU School of Medicine Researchers currently have access to two national datasets through the RWE DataLab:

  • RWE Psychiatry Data
    The IU School of Medicine Psych Dataset is one of the largest in the U.S., encompassing more than 4.8 million patients with up to 20 years of longitudinal structured data as well as all clinical notes.

  • RWE Cardiology Data
    Considered one of the richest real-world datasets of its kind in the U.S., the IU School of Medicine Cardiology Dataset contains up to 20 years of longitudinal de-identified data for nearly 3.5 million patients across more than 45 million encounters.

Transforming real-world insights into practice-changing medicine

Available to all IU School of Medicine students, residents and faculty, the RWE DataLab was designed with the goal of accelerating the discovery of meaningful insights into practice-changing research and medicine. IU School of Medicine researchers can utilize the RWE DataLab to build patient cohorts and extract desired data elements from licensed RWE datasets in support of scholarly articles, poster presentations and grant submissions.

Faculty

Rebecca L. Sparks-Thissen, PhD

Associate Professor of Clinical Microbiology & Immunology

Kara Garcia, PhD

Assistant Professor of Radiology & Imaging Sciences

Arthur L. Chlebowski, PhD

Adjunct Associate Professor of Family Medicine

Kevin Jordan, PhD

Adjunct Clinical Associate Professor of Psychiatry

Staff

Faculty Profile Picture Placeholder IUSM Logo

Will Rasch

Program Management Assistant

Research and Engagement

Stone Center faculty work with Indiana University Medical Student Program for Research and Scholarship (IMPRS) to provide guided research and scholarly opportunities, specifically in real-world, evidence-based research. 

Tatiana Aviles, '28
Isaiah Jones, '28
Logan Lively, '28
Uday Lomada, '28

The Scholarly Concentrations program is an optional, co-curricular opportunity that empowers students to explore specialized topics of personal and professional interest alongside the core medical school curriculum. The Quality and Innovation in Health Care scholarly concentration in Evansville allows students to use real-world evidence to identify needs and assess practical solutions to problems in health care.

Contact us

For further information regarding our projects and programs, please do not hesitate to contact our team. We look forward to discussing how we can support your specific needs.

Research in Bipolar Disorder and Other Mood Disorders

The Mary O’Daniel Stone and Bill Stone Center for Child and Adolescent Psychiatry provides a significant shift in funding and research for bipolar disorder in children and adolescents. Through expansion and resource allocations, this vital research is conducted at IU School of Medicine—Indianapolis, enhancing current bipolar disorder-related research into the genetics of the disease, the search for biomarkers to provide early diagnosis and understanding of the impacts on the children of adults with bipolar disorder.