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Indiana University School of Medicine
Indiana University School of Medicine
Indiana Center for Biological Microscopy

Publications

Peer reviewed publications resulting from Indiana Center for Biological Microscopy resources are listed by year below. Papers in which images acquired either contributed to the body of the work or appeared as part of the published paper are shown.

  1. Behrouzi, A.;  Xia, H.;  Thompson, E. L.;  Kelley, M. R.; Fehrenbacher, J. C., Oxidative DNA Damage and Cisplatin Neurotoxicity Is Exacerbated by Inhibition of OGG1 Glycosylase Activity and APE1 Endonuclease Activity in Sensory Neurons. Int J Mol Sci 2022, 23 (3).

  2. Bhamidipati, T.;  Kumar, M.;  Verma, S. S.;  Mohanty, S. K.;  Kacar, S.;  Reese, D.;  Martinez, M. M.;  Kamocka, M. M.;  Dunn, K. W.;  Sen, C. K.; Singh, K., Epigenetic basis of diabetic vasculopathy. Front Endocrinol (Lausanne) 2022, 13, 989844.

  3. Canela, V. H.;  Bledsoe, S. B.;  Worcester, E. M.;  Lingeman, J. E.;  El-Achkar, T. M.; Williams, J. C., Jr., Collagen fibrils and cell nuclei are entrapped within Randall's plaques but not in CaOx matrix overgrowth: A microscopic inquiry into Randall's plaque stone pathogenesis. Anat Rec (Hoboken) 2022, 305 (7), 1701-1711.

  4. Canela, V. H.;  Dzien, C.;  Bledsoe, S. B.;  Borofsky, M. S.;  Boris, R. S.;  Lingeman, J. E.;  El-Achkar, T. M.; Williams, J. C., Jr., Human jackstone arms show a protein-rich, X-ray lucent core, suggesting that proteins drive their rapid and linear growth. Urolithiasis 2022, 50 (1), 21-28.

  5. Cokic, I.;  Chan, S. F.;  Guan, X.;  Nair, A. R.;  Yang, H. J.;  Liu, T.;  Chen, Y.;  Hernando, D.;  Sykes, J.;  Tang, R.;  Butler, J.;  Dohnalkova, A.;  Kovarik, L.;  Finney, R.;  Kali, A.;  Sharif, B.;  Bouchard, L. S.;  Gupta, R.;  Krishnam, M. S.;  Vora, K.;  Tamarappoo, B.;  Howarth, A. G.;  Kumar, A.;  Francis, J.;  Reeder, S. B.;  Wood, J. C.;  Prato, F. S.; Dharmakumar, R., Intramyocardial hemorrhage drives fatty degeneration of infarcted myocardium. Nat Commun 2022, 13 (1), 6394.

  6. Collins, K. S.;  Eadon, M. T.;  Cheng, Y. H.;  Barwinska, D.;  Melo Ferreira, R.;  McCarthy, T. W.;  Janosevic, D.;  Syed, F.;  Maier, B.;  El-Achkar, T. M.;  Kelly, K. J.;  Phillips, C. L.;  Hato, T.;  Sutton, T. A.; Dagher, P. C., Alterations in Protein Translation and Carboxylic Acid Catabolic Processes in Diabetic Kidney Disease. Cells 2022, 11 (7).

  7. Dunn, K. W.;  Hall, A. M.; Molitoris, B. A., Editorial: Proceedings of the 2021 Indiana O'Brien Center Microscopy Workshop. Front Physiol 2022, 13, 891526.

  8. Eadon, M. T.;  Dagher, P. C.; El-Achkar, T. M., Cellular and molecular interrogation of kidney biopsy specimens. Curr Opin Nephrol Hypertens 2022, 31 (2), 160-167.

  9. El-Achkar, T. M.;  Winfree, S.;  Talukder, N.;  Barwinska, D.;  Ferkowicz, M. J.; Al Hasan, M., Tissue Cytometry With Machine Learning in Kidney: From Small Specimens to Big Data. Front Physiol 2022, 13, 832457.

  10. George, R. M.;  Guo, S.;  Firulli, B. A.;  Rubart, M.; Firulli, A. B., Neonatal Deletion of Hand1 and Hand2 within Murine Cardiac Conduction System Reveals a Novel Role for HAND2 in Rhythm Homeostasis. J Cardiovasc Dev Dis 2022, 9 (7).

  11. Hansen, J.;  Sealfon, R.;  Menon, R.;  Eadon, M. T.;  Lake, B. B.;  Steck, B.;  Anjani, K.;  Parikh, S.;  Sigdel, T. K.;  Zhang, G.;  Velickovic, D.;  Barwinska, D.;  Alexandrov, T.;  Dobi, D.;  Rashmi, P.;  Otto, E. A.;  Rivera, M.;  Rose, M. P.;  Anderton, C. R.;  Shapiro, J. P.;  Pamreddy, A.;  Winfree, S.;  Xiong, Y.;  He, Y.;  de Boer, I. H.;  Hodgin, J. B.;  Barisoni, L.;  Naik, A. S.;  Sharma, K.;  Sarwal, M. M.;  Zhang, K.;  Himmelfarb, J.;  Rovin, B.;  El-Achkar, T. M.;  Laszik, Z.;  He, J. C.;  Dagher, P. C.;  Valerius, M. T.;  Jain, S.;  Satlin, L. M.;  Troyanskaya, O. G.;  Kretzler, M.;  Iyengar, R.; Azeloglu, E. U., A reference tissue atlas for the human kidney. Sci Adv 2022, 8 (23), eabn4965.

  12. Jones, N. M.;  Sysol, J. R.;  Singla, S.;  Smith, P.;  Sandusky, G. E.;  Wang, H.;  Natarajan, V.;  Dudek, S. M.; Machado, R. F., Cortactin loss protects against hemin-induced acute lung injury in sickle cell disease. Am J Physiol Lung Cell Mol Physiol 2022, 322 (6), L890-l897.

  13. Jose, L.;  Androphy, E. J.; DeSmet, M., SETD6 Regulates E2-Dependent Human Papillomavirus Transcription. J Virol 2022, 96 (22), e0129522.

  14. Joshi, J.;  Xu, B.;  Rubart, M.;  Chang, Y.;  Bao, X.;  Chaliki, H. P.;  Scott, L. R.; Zhu, W., Optogenetic Control of Engrafted Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes in Live Mice: A Proof-of-Concept Study. Cells 2022, 11 (6).

  15. Kanginakudru, S.;  Gilson, T.;  Jose, L.; Androphy, E. J., Effects of Caffeine, a DNA Damage Response Inhibitor, on Papillomavirus Genome Replication. Pathogens 2022, 11 (11).

  16. LaFavers, K. A.; El-Achkar, T. M., Systemic Effects of Tamm-Horsfall Protein in Kidney Disease. Semin Nephrol 2022, 42 (3), 151277.

  17. LaFavers, K. A.;  Hage, C. A.;  Gaur, V.;  Micanovic, R.;  Hato, T.;  Khan, S.;  Winfree, S.;  Doshi, S.;  Moorthi, R. N.;  Twigg, H.;  Wu, X. R.;  Dagher, P. C.;  Srour, E. F.; El-Achkar, T. M., The kidney protects against sepsis by producing systemic uromodulin. Am J Physiol Renal Physiol 2022, 323 (2), F212-f226.

  18. LaFavers, K. A.;  Micanovic, R.;  Sabo, A. R.;  Maghak, L. A.; El-Achkar, T. M., Evolving Concepts in Uromodulin Biology, Physiology, and Its Role in Disease: a Tale of Two Forms. Hypertension 2022, 79 (11), 2409-2418.

  19. Liu, J.;  Nair, V.;  Zhao, Y. Y.;  Chang, D. Y.;  Limonte, C.;  Bansal, N.;  Fermin, D.;  Eichinger, F.;  Tanner, E. C.;  Bellovich, K. A.;  Steigerwalt, S.;  Bhat, Z.;  Hawkins, J. J.;  Subramanian, L.;  Rosas, S. E.;  Sedor, J. R.;  Vasquez, M. A.;  Waikar, S. S.;  Bitzer, M.;  Pennathur, S.;  Brosius, F. C.;  De Boer, I.;  Chen, M.;  Kretzler, M.; Ju, W., Multi-Scalar Data Integration Links Glomerular Angiopoietin-Tie Signaling Pathway Activation With Progression of Diabetic Kidney Disease. Diabetes 2022, 71 (12), 2664-2676.

  20. Lutnick, B.;  Manthey, D.;  Becker, J. U.;  Ginley, B.;  Moos, K.;  Zuckerman, J. E.;  Rodrigues, L.;  Gallan, A. J.;  Barisoni, L.;  Alpers, C. E.;  Wang, X. X.;  Myakala, K.;  Jones, B. A.;  Levi, M.;  Kopp, J. B.;  Yoshida, T.;  Zee, J.;  Han, S. S.;  Jain, S.;  Rosenberg, A. Z.;  Jen, K. Y.; Sarder, P., A user-friendly tool for cloud-based whole slide image segmentation with examples from renal histopathology. Commun Med (Lond) 2022, 2, 105.

  21. Melo Ferreira, R.;  Gisch, D. L.; Eadon, M. T., Spatial transcriptomics and the kidney. Curr Opin Nephrol Hypertens 2022, 31 (3), 244-250.

  22. Menon, R.;  Bomback, A. S.;  Lake, B. B.;  Stutzke, C.;  Grewenow, S. M.;  Menez, S.;  D'Agati, V. D.; Jain, S., Integrated single-cell sequencing and histopathological analyses reveal diverse injury and repair responses in a participant with acute kidney injury: a clinical-molecular-pathologic correlation. Kidney Int 2022, 101 (6), 1116-1125.

  23. Micanovic, R.;  LaFavers, K. A.;  Patidar, K. R.;  Ghabril, M. S.;  Doud, E. H.;  Mosley, A. L.;  Sabo, A. R.;  Khan, S.; El-Achkar, T. M., The kidney releases a nonpolymerizing form of uromodulin in the urine and circulation that retains the external hydrophobic patch domain. Am J Physiol Renal Physiol 2022, 322 (4), F403-f418.

  24. Molitoris, B. A.;  Sandoval, R. M.; Wagner, M. C., Intravital Multiphoton Microscopy as a Tool for Studying Renal Physiology, Pathophysiology and Therapeutics. Front Physiol 2022, 13, 827280.

  25. Molitoris, B. A.;  Sandoval, R. M.;  Yadav, S. P. S.; Wagner, M. C., Albumin uptake and processing by the proximal tubule: physiological, pathological, and therapeutic implications. Physiol Rev 2022, 102 (4), 1625-1667.

  26. Mulcrone, P. L.;  Zhang, J.;  Pride, P. M.;  Lam, A. K.;  Frabutt, D. A.;  Ball-Kell, S. M.; Xiao, W., Genomic Designs of rAAVs Contribute to Pathological Changes in the Livers and Spleens of Mice. Adv Cell Gene Ther 2022, 2022.

  27. Nie, J.;  Ueda, Y.;  Solivais, A. J.; Hashino, E., CHD7 regulates otic lineage specification and hair cell differentiation in human inner ear organoids. Nat Commun 2022, 13 (1), 7053.

  28. Noori-Dokht, H.;  Joukar, A.;  Karnik, S.;  Williams, T.;  Trippel, S. B.; Wagner, D. R., A Photochemical Crosslinking Approach to Enhance Resistance to Mechanical Wear and Biochemical Degradation of Articular Cartilage. Cartilage 2022, 13 (3), 19476035221093064.

  29. Panariello, B. H. D.;  Cavichioli, E. A. M.;  Sochacki, S. F.;  Gandini Junior, L. G.; Duarte, S., Effect of blue light plus chlorhexidine therapy on Streptococcus mutans biofilm and its regrowth in an in vitro orthodontic model. Am J Orthod Dentofacial Orthop 2022, 161 (1), 103-114.

  30. Rosin, D. L.;  Hall, J. P.;  Zheng, S.;  Huang, L.;  Campos-Bilderback, S.;  Sandoval, R.;  Bree, A.;  Beaumont, K.;  Miller, E.;  Larsen, J.;  Hariri, G.;  Kaila, N.;  Encarnacion, I. M.;  Gale, J. D.;  van Elsas, A.;  Molitoris, B. A.; Okusa, M. D., Human Recombinant Alkaline Phosphatase (Ilofotase Alfa) Protects Against Kidney Ischemia-Reperfusion Injury in Mice and Rats Through Adenosine Receptors. Front Med (Lausanne) 2022, 9, 931293.

  31. Sabo, A. R.;  Winfree, S.;  Bledsoe, S. B.;  Phillips, C. L.;  Lingeman, J. E.;  Eadon, M. T.;  Williams, J. C., Jr.; El-Achkar, T. M., Label-free imaging of non-deparaffinized sections of the human kidney to determine tissue quality and signatures of disease. Physiol Rep 2022, 10 (3), e15167.

  32. Saxena, V.;  Arregui, S.;  Kamocka, M. M.;  Hains, D. S.; Schwaderer, A., MAP3K7 is an innate immune regulatory gene with increased expression in human and murine kidney intercalated cells following uropathogenic Escherichia coli exposure. J Cell Biochem 2022, 123 (11), 1817-1826.

  33. So, J.;  Taleb, S.;  Wann, J.;  Strobel, O.;  Kim, K.; Roh, H. C., Chronic cAMP activation induces adipocyte browning through discordant biphasic remodeling of transcriptome and chromatin accessibility. Mol Metab 2022, 66, 101619.

  34. Tonon, C. C.;  Panariello, B.;  Chorilli, M.;  Spolidorio, D. M. P.; Duarte, S., Effect of curcumin-loaded photoactivatable polymeric nanoparticle on peri-implantitis-related biofilm. Photodiagnosis Photodyn Ther 2022, 40, 103150.

  35. Ueda, Y.;  Moore, S. T.; Hashino, E., Directed Differentiation of Human Pluripotent Stem Cells into Inner Ear Organoids. Methods Mol Biol 2022, 2520, 135-150.

  36. Ueoka, A.;  Sung, Y. L.;  Liu, X.;  Rosenberg, C.;  Chen, Z.;  Everett, T. H. t.;  Rubart, M.;  Tisdale, J. E.; Chen, P. S., Testosterone does not shorten action potential duration in Langendorff-perfused rabbit ventricles. Heart Rhythm 2022.

  37. Wagner, L. E.;  Melnyk, O.;  Duffett, B. E.; Linnemann, A. K., Mouse models and human islet transplantation sites for intravital imaging. Front Endocrinol (Lausanne) 2022, 13, 992540.

  38. Wagner, M. C.;  Sandoval, R. M.;  Campos-Bilderback, S. B.; Molitoris, B. A., Using 2-Photon Microscopy to Quantify the Effects of Chronic Unilateral Ureteral Obstruction on Glomerular Processes. J Vis Exp 2022,  (181).

  39. Williams, J. C., Jr.;  Al-Awadi, H.;  Muthenini, M.;  Bledsoe, S. B.;  El-Achkar, T.;  Evan, A. P.;  Coe, F.;  Lingeman, J. E.; Worcester, E. M., Stone Morphology Distinguishes Two Pathways of Idiopathic Calcium Oxalate Stone Pathogenesis. J Endourol 2022, 36 (5), 694-702.

  40. Winfree, S.;  Al Hasan, M.; El-Achkar, T. M., Profiling Immune Cells in the Kidney Using Tissue Cytometry and Machine Learning. Kidney360 2022, 3 (5), 968-978.

  1. Barwinska, D.;  El-Achkar, T. M.;  Melo Ferreira, R.;  Syed, F.;  Cheng, Y. H.;  Winfree, S.;  Ferkowicz, M. J.;  Hato, T.;  Collins, K. S.;  Dunn, K. W.;  Kelly, K. J.;  Sutton, T. A.;  Rovin, B. H.;  Parikh, S. V.;  Phillips, C. L.;  Dagher, P. C.; Eadon, M. T., Molecular characterization of the human kidney interstitium in health and disease. Sci Adv 2021, 7 (7).

  2. Bellchambers, H. M.; Ware, S. M., Loss of Zic3 impairs planar cell polarity leading to abnormal left-right signaling, heart defects and neural tube defects. Hum Mol Genet 2021, 30 (24), 2402-2415.

  3. Black, L. M.;  Farrell, E. R.;  Barwinska, D.;  Osis, G.;  Zmijewska, A. A.;  Traylor, A. M.;  Esman, S. K.;  Bolisetty, S.;  Whipple, G.;  Kamocka, M. M.;  Winfree, S.;  Spangler, D. R.;  Khan, S.;  Zarjou, A.;  El-Achkar, T. M.; Agarwal, A., VEGFR3 tyrosine kinase inhibition aggravates cisplatin nephrotoxicity. Am J Physiol Renal Physiol 2021, 321 (6), F675-f688.

  4. Black, L. M.;  Winfree, S.;  Khochare, S. D.;  Kamocka, M. M.;  Traylor, A. M.;  Esman, S. K.;  Khan, S.;  Zarjou, A.;  Agarwal, A.; El-Achkar, T. M., Quantitative 3-dimensional imaging and tissue cytometry reveals lymphatic expansion in acute kidney injury. Lab Invest 2021, 101 (9), 1186-1196.

  5. Canela, V. H.;  Bledsoe, S. B.;  Lingeman, J. E.;  Gerber, G.;  Worcester, E. M.;  El-Achkar, T. M.; Williams, J. C., Jr., Demineralization and sectioning of human kidney stones: A molecular investigation revealing the spatial heterogeneity of the stone matrix. Physiol Rep 2021, 9 (1), e14658.

  6. Canela, V. H.;  Bledsoe, S. B.;  Worcester, E. M.;  Lingeman, J. E.;  El-Achkar, T. M.; Williams, J. C., Jr., Collagen fibrils and cell nuclei are entrapped within Randall's plaques but not in CaOx matrix overgrowth: A microscopic inquiry into Randall's plaque stone pathogenesis. Anat Rec (Hoboken) 2021.

  7. Chen, N. X.;  O'Neill, K. D.;  Dominguez, J. M., 2nd; Moe, S. M., Regulation of reactive oxygen species in the pathogenesis of matrix vesicles induced calcification of recipient vascular smooth muscle cells. Vasc Med 2021, 26 (6), 585-594.

  8. Dunn, K. W., Digital Image Analysis Tools Developed by the Indiana O'Brien Center. Front Physiol 2021, 12, 812170.

  9. Dunn, K. W.;  Molitoris, B. A.; Dagher, P. C., The Indiana O'Brien Center for Advanced Renal Microscopic Analysis. Am J Physiol Renal Physiol 2021, 320 (5), F671-f682.

  10. Eadon, M. T.;  Lampe, S.;  Baig, M. M.;  Collins, K. S.;  Melo Ferreira, R.;  Mang, H.;  Cheng, Y. H.;  Barwinska, D.;  El-Achkar, T. M.;  Schwantes-An, T. H.;  Winfree, S.;  Temm, C. J.;  Ferkowicz, M. J.;  Dunn, K. W.;  Kelly, K. J.;  Sutton, T. A.;  Moe, S. M.;  Moorthi, R. N.;  Phillips, C. L.; Dagher, P. C., Clinical, histopathologic and molecular features of idiopathic and diabetic nodular mesangial sclerosis in humans. Nephrol Dial Transplant 2021, 37 (1), 72-84.

  11. El-Achkar, T. M.;  Eadon, M. T.;  Menon, R.;  Lake, B. B.;  Sigdel, T. K.;  Alexandrov, T.;  Parikh, S.;  Zhang, G.;  Dobi, D.;  Dunn, K. W.;  Otto, E. A.;  Anderton, C. R.;  Carson, J. M.;  Luo, J.;  Park, C.;  Hamidi, H.;  Zhou, J.;  Hoover, P.;  Schroeder, A.;  Joanes, M.;  Azeloglu, E. U.;  Sealfon, R.;  Winfree, S.;  Steck, B.;  He, Y.;  D'Agati, V.;  Iyengar, R.;  Troyanskaya, O. G.;  Barisoni, L.;  Gaut, J.;  Zhang, K.;  Laszik, Z.;  Rovin, B. H.;  Dagher, P. C.;  Sharma, K.;  Sarwal, M. M.;  Hodgin, J. B.;  Alpers, C. E.;  Kretzler, M.; Jain, S., A multimodal and integrated approach to interrogate human kidney biopsies with rigor and reproducibility: guidelines from the Kidney Precision Medicine Project. Physiol Genomics 2021, 53 (1), 1-11.

  12. Fang, Y.;  Wang, L.;  Wan, C.;  Sun, Y.;  Van der Jeught, K.;  Zhou, Z.;  Dong, T.;  So, K. M.;  Yu, T.;  Li, Y.;  Eyvani, H.;  Colter, A. B.;  Dong, E.;  Cao, S.;  Wang, J.;  Schneider, B. P.;  Sandusky, G. E.;  Liu, Y.;  Zhang, C.;  Lu, X.; Zhang, X., MAL2 drives immune evasion in breast cancer by suppressing tumor antigen presentation. J Clin Invest 2021, 131 (1).

  13. Ferkowicz, M. J.;  Winfree, S.;  Sabo, A. R.;  Kamocka, M. M.;  Khochare, S.;  Barwinska, D.;  Eadon, M. T.;  Cheng, Y. H.;  Phillips, C. L.;  Sutton, T. A.;  Kelly, K. J.;  Dagher, P. C.;  El-Achkar, T. M.; Dunn, K. W., Large-scale, three-dimensional tissue cytometry of the human kidney: a complete and accessible pipeline. Lab Invest 2021, 101 (5), 661-676.

  14. Garcia, B. A.;  Panariello, B. H. D.;  Freitas-Pontes, K. M.; Duarte, S., Candida biofilm matrix as a resistance mechanism against photodynamic therapy. Photodiagnosis Photodyn Ther 2021, 36, 102525.

  15. Janosevic, D.;  Myslinski, J.;  McCarthy, T. W.;  Zollman, A.;  Syed, F.;  Xuei, X.;  Gao, H.;  Liu, Y. L.;  Collins, K. S.;  Cheng, Y. H.;  Winfree, S.;  El-Achkar, T. M.;  Maier, B.;  Melo Ferreira, R.;  Eadon, M. T.;  Hato, T.; Dagher, P. C., The orchestrated cellular and molecular responses of the kidney to endotoxin define a precise sepsis timeline. Elife 2021, 10.

  16. Melo Ferreira, R.;  Sabo, A. R.;  Winfree, S.;  Collins, K. S.;  Janosevic, D.;  Gulbronson, C. J.;  Cheng, Y. H.;  Casbon, L.;  Barwinska, D.;  Ferkowicz, M. J.;  Xuei, X.;  Zhang, C.;  Dunn, K. W.;  Kelly, K. J.;  Sutton, T. A.;  Hato, T.;  Dagher, P. C.;  El-Achkar, T. M.; Eadon, M. T., Integration of spatial and single-cell transcriptomics localizes epithelial cell-immune cross-talk in kidney injury. JCI Insight 2021, 6 (12).

  17. Miller, S. G.;  Hafen, P. S.;  Law, A. S.;  Springer, C. B.;  Logsdon, D. L.;  O'Connell, T. M.;  Witczak, C. A.; Brault, J. J., AMP deamination is sufficient to replicate an atrophy-like metabolic phenotype in skeletal muscle. Metabolism 2021, 123, 154864.

  18. Panariello, B. H. D.;  Kindler, J. K.;  Spolnik, K. J.;  Ehrlich, Y.;  Eckert, G. J.; Duarte, S., Use of electromagnetic stimulation on an Enterococcus faecalis biofilm on root canal treated teeth in vitro. Sci Rep 2021, 11 (1), 8306.

  19. Ruan, J.;  Zhang, L.;  Hu, D.;  Qu, X.;  Yang, F.;  Chen, F.;  He, X.;  Shen, J.;  Dong, K.;  Sweet, M.;  Sanchez, C.;  Li, D.;  Shou, W.;  Zhou, J.; Cai, C. L., Novel Myh11 Dual Reporter Mouse Model Provides Definitive Labeling and Identification of Smooth Muscle Cells-Brief Report. Arterioscler Thromb Vasc Biol 2021, 41 (2), 815-821.

  20. Saxena, V.;  Gao, H.;  Arregui, S.;  Zollman, A.;  Kamocka, M. M.;  Xuei, X.;  McGuire, P.;  Hutchens, M.;  Hato, T.;  Hains, D. S.; Schwaderer, A. L., Kidney intercalated cells are phagocytic and acidify internalized uropathogenic Escherichia coli. Nat Commun 2021, 12 (1), 2405.

  21. Tonon, C. C.;  Panariello, B. H. D.;  Spolidorio, D. M. P.;  Gossweiler, A. G.; Duarte, S., Antibiofilm effect of ozonized physiological saline solution on peri-implant-related biofilm. J Periodontol 2021, 92 (8), 1151-1162.

  22. Ueda, Y.;  Moore, S. T.; Hashino, E., Directed Differentiation of Human Pluripotent Stem Cells into Inner Ear Organoids. Methods Mol Biol 2021.

  23. Winfree, S.;  Weiler, C.;  Bledsoe, S. B.;  Gardner, T.;  Sommer, A. J.;  Evan, A. P.;  Lingeman, J. E.;  Krambeck, A. E.;  Worcester, E. M.;  El-Achkar, T. M.; Williams, J. C., Jr., Multimodal imaging reveals a unique autofluorescence signature of Randall's plaque. Urolithiasis 2021, 49 (2), 123-135.

  24. Woloshuk, A.;  Khochare, S.;  Almulhim, A. F.;  McNutt, A. T.;  Dean, D.;  Barwinska, D.;  Ferkowicz, M. J.;  Eadon, M. T.;  Kelly, K. J.;  Dunn, K. W.;  Hasan, M. A.;  El-Achkar, T. M.; Winfree, S., In Situ Classification of Cell Types in Human Kidney Tissue Using 3D Nuclear Staining. Cytometry A 2021, 99 (7), 707-721.

  25. Xu, H.;  Van der Jeught, K.;  Zhou, Z.;  Zhang, L.;  Yu, T.;  Sun, Y.;  Li, Y.;  Wan, C.;  So, K. M.;  Liu, D.;  Frieden, M.;  Fang, Y.;  Mosley, A. L.;  He, X.;  Zhang, X.;  Sandusky, G. E.;  Liu, Y.;  Meroueh, S. O.;  Zhang, C.;  Wijeratne, A. B.;  Huang, C.;  Ji, G.; Lu, X., Atractylenolide I enhances responsiveness to immune checkpoint blockade therapy by activating tumor antigen presentation. J Clin Invest 2021, 131 (10).

  26. Yadav, S. P. S.;  Sandoval, R. M.;  Zhao, J.;  Huang, Y.;  Wang, E.;  Kumar, S.;  Campos-Bilderback, S. B.;  Rhodes, G.;  Mechref, Y.;  Molitoris, B. A.; Wagner, M. C., Mechanism of how carbamylation reduces albumin binding to FcRn contributing to increased vascular clearance. Am J Physiol Renal Physiol 2021, 320 (1), F114-f129.

  1. Adhyapok, P.;  Fu, X.;  Sluka, J. P.;  Clendenon, S. G.;  Sluka, V. D.;  Wang, Z.;  Dunn, K.;  Klaunig, J. E.; Glazier, J. A., A computational model of liver tissue damage and repair. PLoS One 2020, 15 (12), e0243451. 

  2. Barwinska, D.;  Ferkowicz, M. J.;  Cheng, Y. H.;  Winfree, S.;  Dunn, K. W.;  Kelly, K. J.;  Sutton, T. A.;  Rovin, B. H.;  Parikh, S. V.;  Phillips, C. L.;  Dagher, P. C.;  El-Achkar, T. M.; Eadon, M. T., Application of Laser Microdissection to Uncover Regional Transcriptomics in Human Kidney Tissue. J Vis Exp 2020,  (160). 

  3. Chen, N. X.;  Srinivasan, S.;  O'Neill, K.;  Nickolas, T. L.;  Wallace, J. M.;  Allen, M. R.;  Metzger, C. E.;  Creecy, A.;  Avin, K. G.; Moe, S. M., Effect of Advanced Glycation End-Products (AGE) Lowering Drug ALT-711 on Biochemical, Vascular, and Bone Parameters in a Rat Model of CKD-MBD. J Bone Miner Res 2020, 35 (3), 608-617. 

  4. Dunn, K. W.;  Martinez, M. M.;  Wang, Z.;  Mang, H. E.;  Clendenon, S. G.;  Sluka, J. P.;  Glazier, J. A.; Klaunig, J. E., Mitochondrial depolarization and repolarization in the early stages of acetaminophen hepatotoxicity in mice. Toxicology 2020, 439, 152464. 

  5. Durbin, M. D.;  O'Kane, J.;  Lorentz, S.;  Firulli, A. B.; Ware, S. M., SHROOM3 is downstream of the planar cell polarity pathway and loss-of-function results in congenital heart defects. Dev Biol 2020, 464 (2), 124-136. 

  6. Elbanna, M.;  Orillion, A. R.;  Damayanti, N. P.;  Adelaiye-Ogala, R.;  Shen, L.;  Miles, K. M.;  Chintala, S.;  Ciamporcero, E.;  Ramakrishnan, S.;  Ku, S. Y.;  Rex, K.;  Caenepeel, S.;  Coxon, A.; Pili, R., Dual Inhibition of Angiopoietin-TIE2 and MET Alters the Tumor Microenvironment and Prolongs Survival in a Metastatic Model of Renal Cell Carcinoma. Mol Cancer Ther 2020, 19 (1), 147-156. 

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