The Division of Clinical Pharmacology and the Indiana Institute for Personalized Medicine offer weekly research seminars as part of the fellowship curriculum. Seminar topics cover research activities in drug metabolism, pharmacokinetics, pharmacodynamics, pharmacogenetics, pharmacoepidemiology and clinical study design. Speakers include faculty, postdoctoral fellows, graduate students, and invited experts in the field of clinical pharmacology.
| Date | Speaker | Presentation Title |
| Jan. 7 | No Seminar | |
| Jan. 14 | No Seminar | |
| Jan. 21 | No Seminar | |
| Jan. 28 | Malek Hajjawi, PhD Postdoctoral Fellow in Medicine Division of Clinical Pharmacology Indiana University School of Medicine |
From Discovery to Development: Leveraging Modeling and Simulation for Alzheimer's Therapeutics |
| Feb. 4 | Lais Da Silva, PhD Assistant Research Professor of Medicine Division of Clinical Pharmacology Indiana University School of Medicine |
From Data to Decisions: Pharmacometrics in Clinical Pharmacology |
| Feb. 11 | No Seminar | |
| Feb. 18 | Aislinn O'Kane, PharmD Postdoctoral Fellow in Medicine Division of Clinical Pharmacology Indiana University School of Medicine |
PBPK modeling of UGT2B10 ontogeny in Pediatrics and Neonates |
| Feb. 25 | No Seminar | |
| March 4 | Nihal El Rouby, PhD, PharmD Assistant Professor University of Cincinnati |
Unlocking the Predictors of Metabolic Syndrome Post Second-Generation Antipsychotics |
| March 11 | Cristian Bernabe, MSc., PhD Assistant Research Professor of Medicine Division of Clinical Pharmacology Indiana University School of Medicine |
Uncovering the role of ABCA7 as a Risk Factor for Alzheimer's Disease |
| March 18 | No Seminar - Week of M&S Symposium | |
| March 25 | Paul Territo, PhD Professor of Medicine Division of Clinical Pharmacology Indiana University School of Medicine |
Assessment of Neurometabolic and Vascular Dysfunction: Development of An Early Translational Diagnostic of Disease Progression |
| April 1 | Yemi Gafari, PharmD, MBA Postdoctoral Fellow in Medicine Division of Clinical Pharmacology Indiana University School of Medicine |
Global Health Challenges: A Tale of Resilience |
| April 8 | Daniel Fehrenbach, PhD Postdoctoral Fellow in Medicine Division of Clinical Pharmacology Indiana University School of Medicine |
ROCKing the Boat: Immune Dysfunction in Hypertension and Heart Failure |
| April 15 | Mofareh Alzahrani, PharmD, BPharm PhD Candidate College of Pharmacy Purdue University |
Minimization of Drug-Induced QT Interval Lengthening in Women |
| April 22 | No Seminar | |
| April 29 | Phoebe Wu, PharmD Postdoctoral Fellow in Medicine Division of Clinical Pharmacology Indiana University School of Medicine |
Pharmacogenetics of Steady State Metabolism, Pharmacokinetics, and Adverse Effects of Voriconazole in Healthy Participants |
| May 6 | Amir Rashidian, PharmD, PhD Postdoctoral Fellow in Medicine Division of Clinical Pharmacology Indiana University School of Medicine |
Understanding of mechanisms of potent bupropion interaction with CYP2D6 substrates: in vitro to in vivo extrapolation |
| May 13 | Ashley Springer, PharmD, MSPGx, RPh Postdoctoral Fellow in Medicine Division of Clinical Pharmacology Indiana University School of Medicine |
Pharmacogenomic Projects |
| May 20 | No Seminar | |
| May 27 |
No Seminar - ASCPT | |
| June 3 | Jiang Bian, PhD Chief Data Scientist, Regenstrief Institute Chief Data Scientist, IU Health Walther and Regenstrief Endowed Chair in Cancer Informatics Associate Dean for Data Science Indiana University School of Medicine |
Real-World Data to Real-World Evidence: Successes, Challenges, and Opportunities in Cancer Research |
| June 10 | David W. Hein, PhD, FAAPE Peter K. Knoefel Endowed Chair of Pharmacology Distinguished University Scholar Professor and Chair, Department of Pharmacology & Toxicology University of Louisville School of Medicine |
Translating research in precision environmental health to pharmacogenomic-guided drug therapy: Example paradigm is the N-acetylation genetic polymorphism |
| June 17 |
No Seminar | |
| June 24 |
Francine J. Azeredo, PhD, BPharm Research Assistant Professor College of Pharmacy University of Florida |
Pharmacometric Innovations in Antimicrobial Therapy |
| July 1 |
No Seminar | |
| July 8 | Evan Rajadhyaksha, MD Resident Appointee Postdoctoral Fellow Division of Clinical Pharmacology Indiana University School of Medicine |
Functional and Histologic Effects of Recurrent UTI in Vesicoureteral Reflux |
| July 15 | No Seminar | |
| July 22 | Emma Tillman, PharmD, PhD Associate Research Professor of Medicine Division of Clinical Pharmacology Indiana University School of Medicine |
Updates on CFTR Modulator Clinical Trials at IU |
| July 29 |
Jumar Etkins, PharmD, MBA Postdoctoral Fellow Division of Clinical Pharmacology Indiana University School of Medicine |
Genotype Specific Safety Profiles and Pharmacokinetics of Cannabidiol in Healthy Subjects |
| Aug. 5 | Michael Eadon, MD Associate Professor of Medicine Indiana University School of Medicine |
Pharmacogenomics of Hypertension: Latest Guidelines and Trials |
| Aug. 12 | No Seminar | |
| Aug. 19 |
Brent Clayton, PhD Associate Research Professor of Medicine Division of Clinical Pharmacology Indiana University School of Medicine |
Enabling Novel Targets for the Development of Alzheimer’s Disease Therapies |
| Aug. 26 | No Seminar | |
| Sept. 2 |
Jason Kim, PharmD Postdoctoral Fellow Division of Clinical Pharmacology Indiana University School of Medicine |
Effect of Efavirenz on CYP2C9 and OATP1B1 Activity in Healthy Volunteers |
| Sept. 9 | Shaoyou Chu, MD, PhD Senior Research Professor of Medicine Division of Clinical Pharmacology Indiana University School of Medicine |
Aging, AD and anti-inflammation drug discovery targeting NF-kB and inflammasome pathways |
| Sept. 16 |
Rebecca Levit, MD Associate Professor Division of Cardiology Emory University |
Neutrophils and hydrogels in cardiac disease and next generation therapeutics |
| Sept. 23 | Tayler B. Smith PhD Graduate Student Medical & Molecular Genetics Indiana University School of Medicine |
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| Sept. 30 | Avi Benitah, PhD Postdoctoral Fellow Division of Clinical Pharmacology Indiana University School of Medicine |
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| Oct. 7 | Chetna Jadala, PhD Postdoctoral Fellow Division of Clinical Pharmacology Indiana University School of Medicine |
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| Oct. 14 | Pathum Weerawarna, PhD Assistant Research Professor of Medicine Division of Clinical Pharmacology Indiana University School of Medicine |
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| Oct. 21 | NO SEMINAR - ACoP Annual Meeting | |
| Oct. 28 | Jess Raffa, PharmD PhD Graduate Student College of Pharmacy Purdue University |
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| Nov. 4 | Debora Gisch, PhD Assistant Research Professor of Medicine Division of Clinical Pharmacology Indiana University School of Medicine |
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| Nov. 11 | TBD | |
| Nov. 18 | Tim Richardson, PhD Senior Research Professor of Medicine Division of Clinical Pharmacology Indiana University School of Medicine |
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| Nov. 25 | No Seminar | |
| Dec. 2 | Suhaas Muralidharan, PharmD PhD Graduate Student College of Pharmacy Purdue University |
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| Dec. 9 | Nitin Charbe, PhD Postdoctoral Fellow Division of Clinical Pharmacology Indiana University School of Medicine |
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| Dec. 16 | Jim Tisdale, PharmD Professor, College of Pharmacy Purdue University Adjunct Professor of Medicine, Division of Clinical Pharmacology Indiana University School of Medicine |
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| Dec. 23 | No Seminar | |
| Dec. 30 | No Seminar |
| Date | Speaker | Presentation Title |
| Jan. 2 | No Seminar | |
| Jan. 9 | No Seminar | |
| Jan. 16 | No Seminar | |
| Jan. 23 | No Seminar | |
| Jan. 30 | Matt Alexander, MD, PhD Assistant Professor of Medicine, Division of Clinical Pharmacology and Cardiovascular Medicine Assistant Professor, Molecular Physiology and Biophysics Vanderbilt University Medical Center |
The yin and yang of cutaneous immune cells in hypertension and kidney disease |
| Feb. 6 | NO SEMINAR - Division Faculty & Administrative Staff Retreat | |
| Feb. 13 | Thiago Bruder do Nascimento, PhD Assistant Professor, Department of Pediatrics University of Pittsburgh School of Medicine |
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| Feb. 20 | No Seminar | |
| Feb. 27 | No Seminar - Annual M&S Symposium |
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| March 5 | Aislinn O'Kane, PharmD Postdoctoral Fellow Division of Clinical Pharmacology Indiana University School of Medicine |
Use of a Physiologically Based Pharmacokinetic (PBPK) Model to Predict Genetic and Allometric Influences on Dexmedetomidine Pharmacokinetics in the Pediatric Population |
| March 12 | No Seminar | |
| March 19 | Megan Shuey, PhD, MS Assistant Professor Division of Genetic Medicine Vanderbilt University Medical Center |
From EMRs to Precision Medicine: Harnessing Big Data for Disease Insights |
| March 26 |
No Seminar -ASCPT Annual Meeting |
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| April 2 | No Seminar | |
| April 9 | Ahmed Abdelhady Abozeid, PhD Director, Clinical Pharmacology, Ex Vivo Intellia Therapeutics |
Pre-Clinical to Clinical Translation of NTLA-2002, an Investigational in vivo CRISPR/Cas9 Therapy for Treatment of Hereditary Angioedema |
| April 16 | No Seminar | |
| April 23 | No Seminar | |
| April 30 | Paul J. Marvar, PhD Associate Professor Department of Pharmacology & Physiology Department of Psychiatry and Behavioral Health The George Washington University |
Cardiovascular Disease Risk in Stress Disorders: Untangling Bidirectionality |
| May 7 | No Seminar | |
| May 14 | Omar El Jordi, PhD Postdoctoral Fellow Division of Clinical Pharmacology Indiana University School of Medicine |
Development of High-throughput Assay for Targeting Inflammasome Formation |
| May 21 | No Seminar | |
| May 28 | No Seminar | |
| June 4 | Josiah Allen, PharmD Pharmacogenomics Pharmacist PGY2 Clinical Pharmacogenomics Pharmacy Residency Program Director St. Elizabeth Healthcare |
When is a hereditary disease gene not a hereditary disease gene? |
| June 11 | Brent Clayton, PhD Associate Research Professor of Medicine Division of Clinical Pharmacology Indiana University School of Medicine |
Small Molecule PLCG2 Activators as a Therapeutic Strategy for the Treatment of Alzheimer's Disease |
| June 18 | No Seminar | |
| June 25 | David W.J. Armstrong, MD, PhD, FRCPC Fellow, Cardiovascular Medicine Merryman Mechanobiology Lab Vanderbilt University Medical Center |
Natriuretic peptides in cardiomyopathies: pathophysiology and therapeutic opportunities |
| July 2 | No Seminar | |
| July 9 | Shaoyou Chu, MD, PhD Senior Research Professor of Medicine Division of Clinical Pharmacology Indiana University School of Medicine |
Drug discovery for the neurodegenerative diseases through targeting activated inflammasome pathway |
| July 16 | Segewkal Hawaze Heruye, PhD Postdoctoral Fellow Division of Clinical Pharmacology Indiana University School of Medicine |
Polymines and Recovery from Acute Kidney Injury |
| July 23 | David M. Haas, MD Robert A. Munsick Professor of Obstetrics & Gynecology Professor of Medicine Indiana University School of Medicine |
The Hoosier Moms Cohort: early pregnancy associations with gestational diabetes and ongoing analyses |
| July 30 | No Seminar | |
| Aug. 6 | Michael Eadon, MD Associate Professor of Medicine Indiana University School of Medicine |
Diabetic Nodular Mesangial Sclerosis: Endothelial Cell Trajectories |
| Aug. 13 | Tayler B. Smith PhD Candidate Medical & Molecular Genetics Indiana University School of Medicine |
Ancestry-Specific Tumor Mutational Burden as a Biomarker for Anti-PD-1 Immunotherapy |
| Aug. 20 | Forum Kamdar, MD, PhD, FACC Assistant Professor of Medicine Department of Medicine, Cardiovascular Division University of Minnesota |
Harnessing Duchenne Muscular Cardiomyopathy Human Models as a Platform for Advancing Therapies |
| Aug. 27 | Emma Tillman, PharmD, PhD Associate Research Professor of Medicine Division of Clinical Pharmacology Indiana University School of Medicine |
Cystic fibrosis transmembrane conductance regulator (CFTR) genetic variants and association with cancer |
| Sept. 3 | No Seminar | |
| Sept. 10 | Ashley Springer, PharmD, MSPGx, BS Postdoctoral Fellow Division of Clinical Pharmacology Indiana University School of Medicine |
Clinical Decision Support Projects |
| Sept. 17 | Emily Mason, PhD Postdoctoral Fellow Division of Clinical Pharmacology Indiana University School of Medicine |
Cell-Based Target Engagement Assays for Alzheimer's Disease (AD) Drug Discovery |
| Sept. 24 | Fatimah Alhurayri, PharmD, MSc PhD Candidate College of Pharmacy Purdue University |
Pharmacokinetic Drug-Drug Interaction of Oral Anticancer Drugs |
| Oct. 1 | No Seminar | |
| Oct. 8 | Zeruesenay Desta, PhD Professor of Medicine Division of Clinical Pharmacology Indiana University School of Medicine |
Implications of Differential Efavirenz Autoinduction of Metabolism |
| Oct. 15 | Omar Aboshady, MD, MSc PhD Candidate College of Pharmacy Purdue University |
An application of model-informed drug development for Ph2 dosing selection |
| Oct. 22 | Peggy Huang PhD Candidate College of Pharmacy Purdue University |
Physiologically-Based Pharmacokinetic Model to Predict CYP3A and OATP1B1 Substrate Disposition in Patients with Fontan-Associated Liver Disease |
| Oct. 29 | Pathum Weerawarna, PhD Assistant Research Professor of Medicine Division of Clinical Pharmacology Indiana University School of Medicine |
Discovery of Potent and Selective Type II Lyn Kinase Inhibitors |
| Nov. 5 | Tyler Shugg, PharmD, PhD Assistant Professor of Medicine Division of Clinical Pharmacology Indiana University School of Medicine |
Endogenous Biomarkers for Drug Disposition: Emerging Tool or Science Fiction? |
| Nov. 12 | No Seminar - ACoP Annual Meeting | |
| Nov. 19 | Tim Richardson, PhD Senior Research Professor of Medicine Division of Clinical Pharmacology Indiana University School of Medicine |
Alzheimer's Drug Discovery Research at IUSM: TREAT-AD Center Update 2024 |
| Nov. 26 | No Seminar | |
| Dec. 3 | No Seminar | |
| Dec. 10 | Jim Tisdale, PharmD Professor, College of Pharmacy, Purdue University Adjunct Professor of Medicine, Division of Clinical Pharmacology, Indiana University School of Medicine |
Drug-Induced QT Interval Prolongation and Arrhythmias in Patients with Heart Failure |
| Dec. 17 | Syed Zaidi, PharmD, PhD Postdoctoral Fellow Division of Clinical Pharmacology Indiana University School of Medicine |
Obstetrics Pharmacology: A Journey from Mice to Humans |
| Dec. 24 | No Seminar |
| Date | Speaker | Presentation Title |
| Jan. 3 | No Seminar | |
| Jan. 10 | No Seminar | |
| Jan. 17 | No Seminar | |
| Jan. 24 | Drs. Emma Tillman & Mary Wermuth Indiana University School of Medicine |
Teamwork makes the dream work: Collaboration on an interesting patient case |
| Jan. 31 | Yaseen Abbasi, PhD Postdoctoral Fellow Division of Clinical Pharmacology Indiana University School of Medicine |
Opioid Literature Review and PBPK Lactation Model of Gabapentin |
| Feb. 7 | No Seminar | |
| Feb. 14 | No Seminar | |
| Feb. 21 | Bo Cao, PhD T32 Postdoctoral Fellowship Candidate Xavier University of Louisiana |
Mechanisms and Clinical Implementations of Interplay Between Androgen Receptor and Its Splice Variants |
| Feb. 28 | Anita Bellail, PhD Assistant Professor of Pathology & Laboratory Medicine Indiana University School of Medicine |
Development of SUMO1 Small Molecule Degraders as the First-in-Class Anticancer drugs through entrepreneurship |
| March 7 | Ashley Springer T32 Postdoctoral Fellowship Candidate Manchester University |
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| March 14 | No Seminar | |
| March 21 | No Seminar - ASCPT Annual Meeting | |
| March 28 | No Seminar | |
| April 4 |
Drs. Gary Mo & Maria Posada |
Prediction of Human Pharmacokinetics and Doses to Inform First in Human Studies |
| April 11 | No Seminar | |
| April 18 | No Seminar | |
| April 25 | Murugesh Kandasamy, PhD Postdoctoral Fellow Division of Clinical Pharmacology Indiana University School of Medicine |
Pharmacokinetics of SHIP1 inhibitors in a mouse model of Alzheimer’s disease |
| May 2 | Todd Skaar, PhD Professor of Medicine Division of Clinical Pharmacology Indiana University School of Medicine |
Updates on implementing pharmacogenetic testing at IU |
| May 9 | Nick Powell, PharmD Assistant Research Professor of Medicine Division of Clinical Pharmacology Indiana University School of Medicine |
Pulling the Thread: Follow-up Research of a Putative mirSNP in Angiotensinogen |
| May 16 | Lauren A. Bell, MD, MPH Postdoctoral Fellow Division of Clinical Pharmacology Indiana University School of Medicine |
Unintentional Adolescent Overdose: Recent Trends and Harm Reduction Approaches |
| May 23 | Darius Meiman, PharmD Postdoctoral Fellow Division of Clinical Pharmacology Indiana University School of Medicine |
Predicting the Effect of Renal Function on Systemic Clearance: Is a Simple Scaling Method Sufficient? |
| May 30 | No Seminar | |
| June 6 | Debora Gisch, PhD Postdoctoral Fellow Division of Clinical Pharmacology Indiana University School of Medicine |
The cell-type and region-specific chromatin landscape of the kidney in health and adaptive injury |
| June 13 | Brent Clayton, PhD Associate Research Professor of Medicine Division of Clinical Pharmacology Indiana University School of Medicine |
Small Molecule PLCG2 Activators as a Therapeutic Strategy for the Treatment of Alzheimer’s Disease |
| June 20 | Aislinn O'Kane, PharmD Postdoctoral Fellow Division of Clinical Pharmacology Indiana University School of Medicine |
The Development of PBPK Model for Dexmedetomidine in Pediatric Patients |
| June 27 | No Seminar | |
| July 4 | No Seminar | |
| July 11 | No Seminar | |
| July 18 | No Seminar | |
| July 25 | No Seminar | |
| Aug. 1 | Chetna Jadala, PhD Postdoctoral Fellow Division of Clinical Pharmacology Indiana University School of Medicine |
PI3CK2A Kinase Inhibitors for Triple Negative Breast Cancer: Design, Synthesis, and Therapeutic Evaluation |
| Aug. 8 | No Seminar | |
| Aug. 15 | No Seminar | |
| Aug. 22 | Michael Eadon, MD Associate Professor of Medicine Indiana University School of Medicine |
A Cellular and Molecular Atlas of the Kidney |
| Aug. 29 | Sara Quinney, PharmD, PhD Professor of Obstetrics & Gynecology Indiana University School of Medicine |
The Maternal Pediatric PRecision in Therapeutics (MPRINT) Hub |
| Sept. 5 | No Seminar | |
| Sept. 12 | Tyler Shugg, PharmD, PhD Assistant Research Professor of Medicine Division of Clinical Pharmacology Indiana University School of Medicine |
Advancing Precision Medicine in Clinical Oncology |
| Sept. 19 | Allison E. Norlander, PhD Assistant Professor of Anatomy, Cell Biology & Physiology Indiana University School of Medicine |
Mitigating Immune-Mediated Inflammation in Hypertension |
| Sept. 26 | No Seminar | |
| Oct. 3 | Pathum Weerawarna, PhD Assistant Research Professor of Medicine Division of Clinical Pharmacology Indiana University School of Medicine |
Potent and Selective Small-Molecule Tool Compounds to Probe the Role of Lyn in Alzheimer's Disease |
| Oct. 10 | Gerald So, PharmD Postdoctoral Fellow Division of Clinical Pharmacology Indiana University School of Medicine |
Drug-Gene-Nutraceutical Interactions of Cannabidiol and Tacrolimus |
| Oct. 17 | Michael M. Attah, PharmD (RPh), MS PhD Candidate Clinical Pharmaceutical Science Purdue University |
Enoxaparin Pharmacokinetics and Dose Optimization in Neonates and Infants using Real World Data |
| Oct. 24 | Emily Mason, PhD Postdoctoral Fellow Division of Clinical Pharmacology Indiana University School of Medicine |
Cell-Based Target Engagement Assays for Alzheimer’s Disease (AD) Drug Discovery |
| Oct. 31 | Min Yue PhD Candidate College of Pharmacy Purdue University |
Reducing the Risk of Drug-Induced QT Interval Lengthening: Population PK/PD Modeling |
| Nov. 7 | No Seminar - Annual American Conference on Pharmacometrics | |
| Nov. 14 | Elizabeth Rowe, PhD Postdoctoral Fellow Division of Clinical Pharmacology Indiana University School of Medicine |
Escitalopram and Citalopram Persistence and CYP2C19 Metabolizer Status: Data from the UK Biobank |
| Nov. 21 | No Seminar | |
| Nov. 28 | Omar Aboshady, MD, MSc PhD Candidate College of Pharmacy Purdue University |
Characterization of a genetic link between PREGnancy progesterone metabolite exposure and CARDiac repolarization: PREG-CARD Study |
| Dec. 5 | Timothy Richardson, PhD Senior Research Professor of Medicine Division of Clinical Pharmacology Indiana University School of Medicine |
Collaborative Efforts in Alzheimer's Research: The TREAT-AD Center's Renewed Approach to Enabling the Next Generation of Drug Targets and Biomarkers |
| Dec. 12 | James E. Tisdale, PharmD Professor, Department of Pharmacy Practice, Purdue University Adjunct Professor, Division of Clinical Pharmacology, Indiana University School of Medicine |
Rhythm Blues: Prevention and Management of Selected Arrhythmias |
| Dec. 19 | John T. Callaghan, MD, PhD Associate Professor of Medicine Division of Clinical Pharmacology Indiana University School of Medicine |
Precision Medicine Delivery Unveiled: Case Study Exposes |
| Dec. 26 | No Seminar |
| Date | Speaker | Presentation Title |
| Jan. 4 | No Seminar | |
| Jan. 11 | No Seminar | |
| Jan. 18 | Thomas D. Nolin, PharmD, PhD Associate Dean for Research and Sponsored Programs Director, Small Molecule Biomarker Core Associate Professor of Pharmacy and Therapeutics University of Pittsburgh School of Pharmacy |
Pursuing Improved Drug Development and Use in CKD: Insights into Nonrenal and Extracorporeal Clearance |
| Jan. 25 | Todd Skaar, PhD Professor of Medicine Division of Clinical Pharmacology Indiana University School of Medicine |
Update on Pharmacogenomics discovery and implementation |
| Feb. 1 | No Seminar | |
| Feb. 8 | No Seminar | |
| Feb. 15 | No Seminar - Annual M&S Symposium | |
| Feb. 22 | No Seminar | |
| March 1 | No Seminar | |
| March 8 | Ricardo Melo Ferreria, PhD Postdoctoral Fellow Division of Clinical Pharmacology Indiana University School of Medicine |
Kidney Real Estate: The search for the best neighborhood |
| March 15 | No Seminar - ASCPT Annual Meeting | |
| March 22 | Elizabeth Rowe, PhD Postdoctoral Fellow Division of Clinical Pharmacology Indiana University School of Medicine |
Pharmacogenomics and Antidepressant Prescribing Patterns in Advanced Cancer Patients |
| March 29 | Wilberforce Osei PhD Candidate Indiana University School of Medicine |
Assess the feasibility of using somatic WES data to call germline PGx genotypes |
| April 5 | Christopher Bartlett, PhD Associate Professor of Pediatrics College of Medicine The Ohio State University |
EHR Data is Better Together: From Institutional Silos into Strengths |
| April 12 | Nick Powell, PharmD Postdoctoral Fellow Division of Clinical Pharmacology Indiana University School of Medicine |
CYP2C19 is Downregulated in NAFLD |
| April 19 | Cynthia Harris, PharmD Principal Research Scientist, Medical Development, Immunology Eli Lilly and Company |
Precision Guiding Dosing of Infliximab |
| April 26 | Debora Gisch, PhD Postdoctoral Fellow Division of Clinical Pharmacology Indiana University School of Medicine |
DNA methylation in renal compartment |
| May 3 | Victoria Pratt, PhD, FACMG VP Molecular Diagnostics Quality Assessments Optum Genomics Adjunct Professor, Medical and Molecular Genetics Indiana University School of Medicine |
AMP’s Recommendations for Clinical TPMP/NUDT15 Allele Testing |
| May 10 | Nadia Bamfo, PharmD Postdoctoral Fellow Division of Clinical Pharmacology Indiana University School of Medicine |
Clinical Study on Steady State PK of Dolutegravir/Rilpivirine (Fixed Dose Combination) in ESRD Patients Requiring Hemodialysis (HD) |
| May 17 | No Seminar | |
| May 24 | Nick Miles, PharmD Postdoctoral Fellow Division of Clinical Pharmacology Indiana University School of Medicine |
Using PBPK Modeling to investigate the Drug-Drug Interaction between Fluoxetine and Clopidogrel |
| May 31 | No Seminar | |
| June 7 | Rebecca Silvola, PharmD Postdoctoral Fellow Division of Clinical Pharmacology Indiana University School of Medicine |
PopPK Analysis to Estimate Gabapentin Exposure in Breastfed Neonates Immediately Following Cesarean Delivery |
| June 14 | No Seminar | |
| June 21 | Paul Territo, PhD Professor of Medicine Division of Clinical Pharmacology Indiana University School of Medicine |
Pharmacokinetic, Pharmacodynamic, and Transcriptomic Analysis of Chronic Levetiracetam Treatment in 5XFAD Mice: A MODEL-AD Preclinical Testing Core Study |
| June 28 | No Seminar | |
| July 5 | No Seminar | |
| July 12 | David Haas, MD Robert A. Munsick Professor of Obstetrics & Gynecology Indiana University School of Medicine |
The PHI Hoosier Moms Cohort: opportunities for collaboration and analyses for all |
| July 19 | No Seminar | |
| July 26 | Burcin Ekser, MD, PhD Associate Professor of Surgery Director, Transplant Research Director, Transplant Immunology and Xenotransplantation Research Labs Division of Transplant Surgery, Department of Surgery Indiana University School of Medicine |
Advanced in Vitro 3D Human Liver Models |
| Aug. 2 | Blessed Winston Arul Dhas, MD, MBBS Postdoctoral Fellow Division of Clinical Pharmacology Indiana University School of Medicine |
Population Pharmacokinetics of Opioids |
| Aug. 9 | Catherine MT Sherwin, PhD, MPharm, DABCP, FCP, CPI Professor & Vice Chair for Research Director, Pediatric Clinical Pharmacology Department of Pediatrics Professor of Pharmacology & Toxicology Wright State University Boonshoft School of Medicine Dayton Children's Hospital |
Proof is in the pudding: the utilization pharmacokinetics and size variables for children |
| Aug. 16 | Michael Eadon, MD Associate Professor of Medicine Indiana University School of Medicine |
Spatial transcriptomics and the kidney |
| Aug. 23 | No Seminar | |
| Aug. 30 | QiPing Feng, PhD Assistant Professor of Medicine Clinical Pharmacology Vanderbilt University Medical Center |
Pleiotropic effects of lipids and lipid-lowering medications |
| Sept. 6 | No Seminar | |
| Sept. 13 | Chimnonso Onuoha, PharmD Postdoctoral Fellow Division of Clinical Pharmacology Indiana University School of Medicine |
Physiologically Based Pharmacokinetics (PBPK) Modeling to Study Hops Compound 8-Prenylnarinenin (8-PN): Elucidating potential mechanisms underlying drug-hop interactions |
| Sept. 20 | Sara Quinney, PhD Associate Professor or Obstetrics & Gynecology Indiana University School of Medicine |
The Importance of PBPK Model Validation and Reproducibility |
| Sept. 27 | Emily Mason, PharmD Postdoctoral Fellow Division of Clinical Pharmacology Indiana University School of Medicine |
Design & Implementation of Cell-Based Assays for Alzheimer's Disease (AD) Drug Discovery |
| Oct. 4 | Darius Meiman, PharmD Postdoctoral Fellow Division of Clinical Pharmacology Indiana University School of Medicine |
Physiologically Based Pharmacokinetic Model to Assess the Drug-Drug-Gene Interaction Potential of Belzutifan in Combination with Cyclin-Dependent Kinase 4/6 Inhibitors in Healthy Volunteers |
| Oct. 11 | Rachael R. Schulte, MSCI, MD Assistant Professor of Clinical Pediatrics Pediatric Hematology and Oncology Indiana University School of Medicine |
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| Oct. 18 | Tyler Shugg, PharmD, PhD Assistant Research Professor of Medicine Division of Clinical Pharmacology Indiana University School of Medicine |
Precision Medicine Approaches to Optimize Immune Checkpoint Inhibitor Therapy |
| Oct. 25 | Lauren A. Bell, MD, MPH Postdoctoral Fellow Division of Clinical Pharmacology Indiana University School of Medicine |
Denial and Self-Management: How Adolescents and Young Adults Initiate, Escalate, Problematize, and Contemplate Disclosure and Treatment of Opioid Use |
| Nov. 1 | No Seminar - ACoP Annual Meeting | |
| Nov. 8 | Zeruesenay Desta, PhD Professor of Medicine Division of Clinical Pharmacology Indiana University School of Medicine |
CYP2B6: from bench to clinic |
| Nov. 15 | Tim Richardson, PhD Senior Research Professor of Medicine Division of Clinical Pharmacology Indiana University School of Medicine |
Progress of the TREAD-AD Center |
| Nov. 22 | No Seminar | |
| Nov. 29 | Emma Tillman, PhD, PharmD Associate Research Professor of Medicine Division of Clinical Pharmacology Indiana University School of Medicine |
Association of mental health adverse drug reactions with highly effective CFTR modulator therapy |
| Dec. 6 | James Tisdale, PharmD Professor, Purdue University Adjunct Professor of Medicine, Indiana University School of Medicine |
Small-Conductance Calcium-Activated Potassium Current as a Possible Drug Target for Atrial Fibrillation |
| Dec. 13 | Shaoyou Chu, PhD, MD Senior Research Professor of Medicine Division of Clinical Pharmacology Indiana University School of Medicine |
Cellular assays supporting TREAD-AD Center drug discovery projects targeting microglia |
| Dec. 20 | No Seminar | |
| Dec. 27 | No Seminar |
| Date | Speaker | Presentation Title |
| Jan. 5 | No Seminar | |
| Jan. 12 | Larissa Silva, PhD Postdoctoral Fellow Division of Clinical Pharmacology Indiana University School of Medicine |
Maternal Betamethasone pharmacokinetics and Respiratory Distress Syndrome in neonates |
| Jan. 19 | Paul Territo, PhD Senior Research Professor Division of Clinical Pharmacology Indiana University School of Medicine |
MODEL-AD: Development of the Next Generation of Late-Onset Alzheimer’s Disease (LOAD) Models |
| Jan. 26 | Blessed Winston Arul Dhas, MD, MBBS Postdoctoral Fellow Division of Clinical Pharmacology Indiana University School of Medicine |
PK modelling of Methadone in Children undergoing Major Surgery |
| Feb. 2 | Tarun Mapder, PhD Postdoctoral Fellow Division of Clinical Pharmacology Indiana University School of Medicine |
Variability in adaptive immune response and Remdesivir pharmacokinetics in population of SARS-CoV-2 infected within-host models |
| Feb. 9 | No Seminar - Fellows Retreat | |
| Feb, 16 | Peter Kissinger, PhD Professor of Chemistry Purdue Chairman and CEO, Bioanalytical Systems, Inc. Indiana University School of Medicine |
Should we be overcoming the tyranny of averages with dosing by integrating modeling with measuring in individual patients? |
| Feb. 23 | Lindsey Kirkpatrick, DO, PhD Postdoctoral Fellow Division of Clinical Pharmacology Indiana University School of Medicine |
Current Challenges in Drug Quantitation from a Clinician’s View: Can Paper Spray Mass Spectrometry Fill the Gap? |
| March 2 | Yana Vorontsova, PharmD, MBA Postdoctoral Fellow Division of Clinical Pharmacology Indiana University School of Medicine |
Development of a Natural Language Processing Machine to Identify Opioid Use Disorder in Electronic Health Records |
| March 9 | NO SEMINAR - ASCPT | |
| March 16 | NO SEMINAR; CANCELLED | |
| March 23 | NO SEMINAR - FOURTH YEAR COURSE | |
| March 30 | Elizabeth Rowe, PhD Postdoctoral Fellow Division of Clinical Pharmacology Indiana University School of Medicine |
QT Interval Prolongation and Polypharmacy in Advanced Cancer Patients: Implications for Clinical Trial Eligibility |
| April 6 | Nadia Bamfo, PharmD Postdoctoral Fellow Division of Clinical Pharmacology Indiana University School of Medicine |
PBPK models to predict stereo selective metabolism of bupropion and CYP2D6-mediated DDIs |
| April 13 | Nick Powell , PharmD Postdoctoral Fellow Division of Clinical Pharmacology Indiana University School of Medicine |
Life-Threatening Docetaxel-Induced Pneumonitis in a Patient with Loss-of-Function Variants in CYP3A4, CYP3A5, and ABCC2: A Potential for Genetic Risk Scores |
| April 20 | Alexander B. Niculescu, III, MD, PhD Professor of Psychiatry and Medical Neuroscience Director, INBRAIN and Laboratory of Neurophenomics Indiana University School of Medicine |
Towards Precision Medicine in Psychiatry |
| April 27 | Vicky Pratt, PhD, FACMG Professor of Clinical Medical & Molecular Genetics Indiana University School of Medicine |
AMP’s Recommendations for CYP2D6 Allele Testing |
| May 4 | Marc Rosenman, MD Associate Professor of Pediatrics Northwestern University |
Retrospective EHR methods in support of PGX studies |
| May 11 | Chimnonso Onuoha, PharmD Postdoctoral Fellow Division of Clinical Pharmacology Indiana University School of Medicine |
The utility of miRNA biomarkers in coronary artery disease |
| May 18 | No Seminar - SimCyp | |
| May 25 | Rebecca Silvola, PharmD Postdoctoral Fellow Division of Clinical Pharmacology Indiana University School of Medicine |
PK and transfer of gabapentin during breastfeeding when used to reduce opioids after cesarean delivery |
| June 1 | Nick Miles, PharmD Postdoctoral Fellow Division of Clinical Pharmacology Indiana University School of Medicine |
Modeling the Drug-Drug Interaction of Fluoxetine and Clopidogrel |
| June 8 | Shaoyou Chu, MD, PhD Senior Research Professor Division of Clinical Pharmacology Indiana University School of Medicine |
Cellular assay development supporting AD drug discovery targeting microglia |
| June 15 | No Seminar - Cancelled | |
| June 22 | Reynold Ly, PhD Postdoctoral Fellow Division of Clinical Pharmacology Indiana University School of Medicine |
Lessons and experiences learned from implementing Germline PGx Testing in the IU Precision Genomics Clinic |
| June 29 | No Seminar | |
| July 6 | No Seminar | |
| July 13 | Ricardo Melo Ferreira, PhD Postdoctoral Fellow Division of Clinical Pharmacology Indiana University School of Medicine |
Spatial transcriptomics of kidney injury |
| July 20 | Drs. Takacs, Storey, Kuhn & Krishnan Eli Lilly & Company Indiana University School of Medicine |
Lilly IU School of Medicine/CTSI Strategic Research Partnership - Understanding Autoimmune Disease Therapy through Transcriptome Analysis |
| July 27 | No Seminar | |
| Aug. 3 | No Seminar | |
| Aug. 10 | Tyler Shugg, PharmD, PhD Postdoctoral Fellow Division of Clinical Pharmacology Indiana University School of Medicine |
Ongoing Projects in Pharmacogenetics Discovery and Implementation |
| Aug. 17 | Larissa Silva, PhD Postdoctoral Fellow Division of Clinical Pharmacology Indiana University School of Medicine |
Modeling approaches for oral absorption: the APX3330 example |
| Aug. 24 | David M. Haas, MD Robert A. Munsick Professor of Obstetrics & Gynecology Indiana University School of Medicine |
Studying the impact of environmental pesticides on pregnancy outcomes- the Heartland Study |
| Aug. 31 | Michael T. Eadon, MD Associate Professor of Medicine Indiana University School of Medicine |
An Atlas of Healthy and Inured Kidney Cells |
| Sept. 7 | Prashant Desai, PhD Director, ADME Lilly Corporate Center |
Model-Informed Drug Discovery and Development |
| Sept. 14 | No Seminar | |
| Sept. 21 | Young Jeong, PhD, PharmD Professor Department of Industrial & Physical Pharmacy Purdue University |
Gut bacterial metabolites modulate drug efficacy and toxicity |
| Sept. 28 | Sara Quinney, PharmD, PhD Associate Professor of Obstetrics & Gynecology Indiana University School of Medicine |
Indiana University-Ohio State University Maternal and Pediatric Precision in Therapeutics Data and Model Knowledge Research Coordination Center (MPRINT DMKRCC) |
| Oct. 5 | Emily Mason, PhD Postdoctoral Fellow Division of Clinical Pharmacology Indiana University School of Medicine |
Design and Implementation of Cell-Based Assays for Alzheimer's Disease (AD) Drug Discovery |
| Oct. 12 | Zeruesanay Desta, PhD Professor of Medicine Division of Clinical Pharmacology Indiana University School of Medicine |
Mechanisms and Extent of Bupropion-CYP2D6 interaction |
| Oct. 19 | No Seminar | |
| Oct. 26 | Tarun Mapder, PhD Postdoctoral Fellow Division of Clinical Pharmacology Indiana University School of Medicine |
Multiscale Approaches in Modeling Disease and Therapeutics |
| Nov. 2 | Timothy Richardson, PhD Senior Research Professor of Medicine Division of Clinical Pharmacology Indiana University School of Medicine |
Targeting SHIP1 and PLCG2 and Immunomodulation of Alzheimers Disease. Targeting a Class II PI3K Kinase to Augment Immunotherapy in Cancer |
| Nov. 9 | John T. Callaghan, MD, PhD, MA Associate Dean for VA Research Division of Clinical Pharmacology Indiana University School of Medicine |
MCAS, IMID,…Acronyms of Import? |
| Nov. 16 | Brenda Roseberry Division Manager Preclinical/Clinical—PK, Pharmacology, Pharmacometrics, Biomarkers Carter Mackay |
CV Preparation For Applications and Interviews in the Pharmaceutical Industry |
| Nov. 23 | No Seminar | |
| Nov. 30 | Emma Tillman, PhD, PharmD Associate Research Professor of Medicine Division of Clinical Pharmacology Indiana University School of Medicine |
Identifying the problem is essential to finding a solution: An approach to detecting and preventing adverse drug reactions (ADRs) in children |
| Dec. 7 | James Tisdale, PharmD Professor, College of Pharmacy, Purdue University Adjunct Professor, Division of Clinical Pharmacology, Indiana University School of Medicine |
Sex Hormones, Ventricular Repolarization and Proarrhythmia |
| Dec. 14 | Rolf Kreutz, MD Associate Professor of Clinical Medicine Indiana University School of Medicine |
Personalizing Antithrombotic Therapy in Interventional Cardiology: Finding the Right Balance |
| Dec. 21 | No Seminar | |
| Dec. 28 | No Seminar |
| Date | Speaker | Presentation Title |
| Jan. 7 | No Seminar | |
| Jan. 14 | No Seminar | |
| Jan. 21 | No Seminar | |
| Jan. 28 | No Seminar | |
| Feb. 4 | No Seminar | |
| Feb. 11 | Saugat Adhikari PhD Candidate College of Pharmacy Purdue University |
Designing combination drug regimens to improve glioblastoma chemotherapy: A pharmacokinetic pharmacodynamic modeling approach |
| Feb. 18 | No Seminar | |
| Feb. 25 | Ryan S. Funk, PharmD, PhD Assistant Professor of Pharmacy Practice University of Kansas Medical Center |
A Clinical Pharmacologists Approach to the Identification of Molecular Biomarkers of Methotrexate Response in Juvenile Idiopathic Arthritis |
| March 3 | Nianjun Liu, PhD Interim Department Co-Chair, Epidemiology and Biostatistics Professor Indiana University |
Genetics of Warfarin Dose Response |
| March 10 | Yana Vorontsova, PharmD Postdoctoral Fellow Division of Clinical Pharmacology Indiana University School of Medicine |
Pharmacokinetics of Buccal vs Vaginal Misoprostol for Labor Induction at Term |
| March 17 | No Seminar - ASCPT | |
| March 24 | No Seminar - 4th Year Course | |
| March 31 | CANCELLED - COVID 19 | |
| April 7 | CANCELLED - COVID 19 | |
| April 14 | Victoria Pratt, PhD Professor of Clinical Medical & Molecular Genetics Director of Pharmacogenomics and Molecular Genetics Laboratories Indiana University School of Medicine |
Establishing Pharmacogenetic Clinical Testing Panels |
| April 21 | No Seminar | |
| April 28 | Ashley E. Rawson, MD Postdoctoral Fellow Division of Clinical Pharmacology Indiana University School of Medicine |
Using Zebrafish to Identify Potential Genetic Targets in Kidney Infection |
| May 5 | No Seminar | |
| May 12 | No Seminar | |
| May 19 | Shaoyou Chu, PhD Senior Research Professor of Medicine Division of Clinical Pharmacology Indiana University School of Medicine |
Cellular pharmacology aspect of antibody drug conjugate discovery |
| May 26 | No Seminar | |
| June 2 | Eric A. Benson, MD, PhD Assistant Professor of Medicine Division of Clinical Pharmacology Indiana University School of Medicine |
Blood Circulating Extracellular Kinetics from Assay Development to 3 Compartment Model |
| June 9 | Anh Duong, PharmD Postdoctoral Fellow Division of Clinical Pharmacology Indiana University School of Medicine |
Prediction of Voriconazole Drug-Gene and Drug-Drug-Gene Interaction Using a Physiologically Based Pharmacokinetic (PBPK) Model |
| June 16 | Maayan Leroy-Melamed, MD Postdoctoral Fellow Adolescent Medicine & Division of Clinical Pharmacology Indiana University School of Medicine |
Provider Views on Sexual and Reproductive Health for Adolescent and Young Adults with Sickle Cell Disease |
| June 23 | CANCELLED - COVID 19 | |
| June 30 | David M. Haas, MD Robert A. Munsick Professor of Obstetrics & Gynecology Department of Obstetrics & Gynecology Indiana University School of Medicine |
Cardiovascular Disease in Pregnancy: What does it mean for long-term health and how can research improve outcomes? |
| July 7 | No Seminar | |
| July 14 | J. Thomas Callaghan, MD, PhD & Richard Bergstrom, PhD Division of Clinical Pharmacology Indiana University School of Medicine |
Clinical Studies Experimental Design’s and the Foibles of Research | Lessons from COVID-19 / SARS-CoV-2 Researc |
| July 21 | No Seminar | |
| July 28 | Timothy I. Richardson, PhD Senior Research Professor of Medicine Department of Obstetrics & Gynecology Indiana University School of Medicine |
A Medicinal Chemist’s Perspective on Translational Research • Introduction to the IU School of Medicine-Purdue TREAT-AD Center • Defining Target Engagement at an Orphan Nuclear Receptor for the Treatment of Autoimmunity |
| Aug. 4 | No Seminar | |
| Aug. 11 | Michael Eadon, MD Assistant Professor of Medicine Division of Nephrology and Division of Clinical Pharmacology Indiana University School of Medicine |
Integration of single cell and spatial transcriptomics in the kidney |
| Aug. 18 | No Seminar | |
| Aug. 25 | No Seminar | |
| Sept. 1 | No Seminar | |
| Sept. 8 | Ebony Shah-Williams PhD Candidate Medical & Molecular Genetics Indiana University School of Medicine |
Diversity, Inclusion and Health /Identifying race specific genetic biomarkers of Taxane Induced Peripheral Neuropathy in African-American breast cancer patients |
| Sept. 15 | Reynold Ly, PhD Postdoctoral Fellow Division of Clinical Pharmacology Indiana University School of Medicine |
Analytical Validation of a Computational Method, Aldy, for Pharmacogenomics Genotyping from Clinical Whole Exome Sequencing |
| Sept. 22 | Robert E. Stratford, PhD Associate Professor of Medicine Director of the Disease and Therapeutic Response Modeling and Simulation Program Indiana University School of Medicine |
Application of Modeling and Simulation to provide insight to existing and new clinical research problems |
| Sept. 29 | Sara K. Quinney, PharmD, PhD Associate Professor Department of Obstetrics & Gynecology Indiana University School of Medicine |
Translational approaches to understanding high-dimensional drug-drug interactions |
| Oct. 6 | Zeruesenay Desta, PhD Professor of Medicine Division of Clinical Pharmacology Indiana University School of Medicine |
Genomic and drug-drug interaction mechanisms of inter-individual difference in drug disposition |
| Oct. 13 | Tyler Shugg, PharmD, PhD Postdoctoral Fellow Department of Obstetrics & Gynecology Indiana University School of Medicine |
Clinical Potential of Repurposing Sequencing Data From a Precision Oncology Clinic to Support Multi-Disciplinary Precision Medicine |
| Oct. 20 | Kimberly Collins, PhD Assistant Scientist in Medicine Division of Clinical Pharmacology Indiana University School of Medicine |
Genotype-guided dosing of hydralazine |
| Oct. 27 | No Seminar | |
| Nov. 3 | Emma M. Tillman, PharmD, PhD Associate Research Professor of Medicine Division of Clinical Pharmacology Indiana University School of Medicine |
Identifying the problem is essential to finding a solution:An approach to detecting and preventing adverse drug reactions (ADRs) in children |
| Nov. 10 | Anthony Raviele, PharmD Postdoctoral Fellow Division of Clinical Pharmacology Indiana University School of Medicine |
In vitro characterization of bictegravir metabolism byUDP-glucuronosyltransferase and cytochrome P450 Enzymes |
| Nov. 17 | Joseph Ipe, PhD Assistant Scientist in Medicine Division of Clinical Pharmacology Indiana University School of Medicine |
Spatial omics to determine tumor heterogeneity and drug penetration |
| Nov. 24 | Brian Overholser, PharmD, FCCP Senior Research Professor of Medicine Associate Professor of Pharmacy Practice Department of Pharmacy Practice, Purdue University |
Calcium/Calmodulin-Dependent Protein Kinase II (CaMKII) Control of Cardiac Repolarization: Potential Mechanism for Arrhythmias during Heart Failure |
| Dec. 1 | James E. Tisdale, PharmD, BCPS, FCCP, FAPhA, FAHA Professor, College of Pharmacy, Purdue University Adjunct Professor, IU School of Medicine |
Assessing the Effects of Drugs on Early Versus Late Ventricular Repolarization |
| Dec. 8 | Todd Skaar, PhD Professor of Medicine Division of Clinical Pharmacology Indiana University School of Medicine |
Multi-disciplinary aspects of the implementation of clinical pharmacogenetic testing |
| Dec. 15 | Nick Powell, PharmD Postdoctoral Fellow Division of Clinical Pharmacology Indiana University School of Medicine |
Identification of miRNA-mRNA interactome in primary hepatocytes and mirSNP functional testing |
| Dec. 22 | Ricardo Ferreira, PhD Postdoctoral Fellow Division of Clinical Pharmacology Indiana University School of Medicine |
Spatial transcriptomic signatures of the human kidney and murine models of kidney injury |
| Dec. 29 | No Seminar |