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Personalized Therapeutics Seminars

Clinical Pharmacology faculty member presenting at a seminar series

The Division of Clinical Pharmacology and the Indiana Institute for Personalized Medicine offer weekly research seminars as part of the fellowship curriculum. Seminar topics cover research activities in drug metabolism, pharmacokinetics, pharmacodynamics, pharmacogenetics, pharmacoepidemiology and clinical study design. Speakers include faculty, postdoctoral fellows, graduate students, and invited experts in the field of clinical pharmacology.

Contact Us

Reach out to Megan Creasser for more information on our weekly research seminars.

Personalized Therapeutics Seminar Schedule

This calendar is subject to change.

January 2, 2024

NO SEMINAR - WINTER BREAK  

January 9, 2024

NO SEMINAR - WINTER BREAK

January 16, 2024

NO SEMINAR - WINTER BREAK

January 23, 2024

NO SEMINAR - WINTER BREAK


January 30, 2024

The yin and yang of cutaneous immune cells in hypertension and kidney disease

Matt Alexander, MD, PhD
Assistant Professor of Medicine, Division of Clinical Pharmacology and Cardiovascular Medicine
Assistant Professor, Molecular Physiology and Biophysics
Vanderbilt University Medical Center


February 6, 2024

NO SEMINAR - Division Faculty & Administrative Staff Retreat


February 13, 2024

Exploring the role of progranulin on blood pressure regulation

Thiago Bruder do Nascimento, PhD
Assistant Professor, Department of Pediatrics
University of Pittsburgh School of Medicine


February 20, 2024

NO SEMINAR


February 27, 2024

NO SEMINAR - 13th Annual Therapeutic Response Modeling Program Symposium


March 5, 2024

Use of a Physiologically Based Pharmacokinetic (PBPK) Model to Predict Genetic and Allometric Influences on Dexmedetomidine Pharmacokinetics in the Pediatric Population

Aislinn O'Kane, PharmD
Postdoctoral Fellow
Division of Clinical Pharmacology
Indiana University School of Medicine


March 12, 2024

NO SEMINAR


March 19, 2024

From EMRs to Precision Medicine: Harnessing Big Data for Disease Insights

Megan Shuey, PhD, MS
Assistant Professor
Division of Genetic Medicine
Vanderbilt University Medical Center

 

March 26, 2024

NO SEMINAR - WEEK of ASCPT


April 2, 2024

NO SEMINAR


April 9, 2024

Pre-Clinical to Clinical Translation of NTLA-2002, an Investigational in vivo CRISPR/Cas9 Therapy for Treatment of Hereditary Angioedema

Ahmed Abdelhady Abozeid, PhD
Director, Clinical Pharmacology, Ex Vivo
Intellia Therapeutics


April 16, 2024

NO SEMINAR


April 23, 2024

NO SEMINAR


April 30, 2024

Cardiovascular Disease Risk in Stress Disorders: Untangling Bidirectionality

Paul J. Marvar, PhD
Associate Professor
Department of Pharmacology & Physiology
Department of Psychiatry and Behavioral Health
The George Washington University


May 7, 2024

NO SEMINAR - CANCELLED


May 14, 2024

Development of High-throughput Assay for Targeting Inflammasome Formation

Omar El Jordi, PhD
Postdoctoral Fellow
Division of Clinical Pharmacology
Indiana University School of Medicine


May 21, 2024

NO SEMINAR


May 28, 2024

NO SEMINAR - WEEK of MEMORIAL DAY


June 4, 2024

When is a hereditary disease gene not a hereditary disease gene?

Josiah Allen, PharmD
Pharmacogenomics Pharmacist
PGY2 Clinical Pharmacogenomics Pharmacy Residency Program Director
St. Elizabeth Healthcare


June 11, 2024

Small Molecule PLCG2 Activators as a Therapeutic Strategy for the Treatment of Alzheimer's Disease

Brent Clayton, PhD
Associate Research Professor of Medicine
Division of Clinical Pharmacology
Indiana University School of Medicine

 

June 18, 2024

NO SEMINAR - WEEK of Juneteenth


June 25, 2024

Natriuretic peptides in cardiomyopathies: pathophysiology and therapetuic opportunities

David W.J. Armstrong, MD, PhD, FRCPC
Fellow, Cardiovascular Medicine
Merryman Mechanobiology Lab
Vanderbilt University Medical Center

 

July 2, 2024

NO SEMINAR - WEEK of Independence Day



July 9, 2024

Drug discovery for the neurodegenerative diseases through targeting activated inflammasome pathway

Shaoyou Chu, MD, PhD
Senior Research Professor of Medicine
Division of Clinical Pharmacology
Indiana University School of Medicine



July 16, 2024

Polymines and Recovery from Acute Kidney Injury

Segewkal Hawaze Heruye, PhD
Postdoctoral Fellow
Division of Clinical Pharmacology
Indiana University School of Medicine


July 16, 2024

The Hoosier Moms Cohort: early pregnancy associations with gestational diabetes and ongoing analyses

David M. Haas, MD
Robert A. Munsick Professor of Obstetrics & Gynecology
Professor of Medicine
Indiana University School of Medicine


July 30, 2024

NO SEMINAR


August 6, 2024

Diabetic Nodular Mesangial Sclerosis: Endothelial Cell Trajectories

Michael Eadon, MD
Associate Professor of Medicine
Indiana University School of Medicine

 

August 13, 2024

Ancestry-Specific Tumor Mutational Burden as a Biomarker for Anti-PD-1 Immunotherapy

Tayler B. Smith
PhD Student
Medical & Molecular Genetics
Division of Clinical Pharmacology, Lab of Dr. Todd Skaar

 

August 20, 2024

Harnessing Duchenne Muscular Cardiomyopathy Human Models as a Platform for Advancing Therapies

Forum Kamdar, MD, PhD, FACC
Assistant Professor of Medicine
Department of Medicine, Cardiovascular Division
University of Minnesota

 

August 27, 2024

Cystic fibrosis transmembrane conductance regulator (CFTR) genetic variants and association with cancer

Emma Tillman, PharmD, PhD
Associate Research Professor of Medicine
Division of Clinical Pharmacology
Indiana University School of Medicine

 

September 3, 2024

NO SEMINAR - WEEK of LABOR DAY

 

September 10, 2024

Clinical Decision Support Projects

Ashley Springer, PharmD, MSPGx, BS
Postdoctoral Fellow
Division of Clinical Pharmacology
Indiana University School of Medicine

 

September 17, 2024

Cell-Based Target Engagement Assays for Alzheimer's Disease (AD) Drug Discovery

Emily Mason, PhD
Postdoctoral Fellow
Division of Clinical Pharmacology
Indiana University School of Medicine

 

September 24, 2024

Pharmacokinetic Drug-Drug Interaction of Oral Anticancer Drugs

Fatimah Alhurayri, PharmD, MSc
PhD Candidate, Purdue College of Pharmacy
Division of Clinical Pharmacology, Lab of Dr. Jim Tisdale

 

October 1, 2024

NO SEMINAR

 

October 8, 2024

Implications of Differential Efavirenz Autoinduction of Metabolism

Zeruesenay Desta, PhD
Professor of Medicine
Division of Clinical Pharmacology
Indiana University School of Medicine

 

October 15, 2024

An application of model-informed drug development for Ph2 dosing selection

Omar Aboshady, MD, MSc
Graduate Student, Purdue College of Pharmacy
Division of Clinical Pharmacology, Lab of Dr. Brian Overholser

 

October 22, 2024

Physiologically-Based Pharmacokinetic Model to Predict CYP3A and OATP1B1 Substrate Disposition in Patients with Fontan-Associated Liver Disease

Peggy Huang
Graduate Student, Purdue College of Pharmacy
Division of Clinical Pharmacology, Lab of Dr. Jim Tisdale


October 29, 2024

Discovery of Potent and Selective Type II Lyn Kinase Inhibitors

Pathum Weerawarna, PhD
Assistant Research Professor of Medicine
Division of Clinical Pharmacology
Indiana University School of Medicine

 

November 5, 2024

Endogenous Biomarkers for Drug Disposition: Emerging Tool or Science Fiction?

Tyler Shugg, PharmD, PhD
Assistant Professor of Medicine
Division of Clinical Pharmacology
Indiana University School of Medicine


November 12, 2024

NO SEMINAR - ACoP


November 19, 2024

Tim Richardson, PhD
Senior Research Professor of Medicine
Division of Clinical Pharmacology
Indiana University School of Medicine


November 26, 2024
NO SEMINAR - WEEK of THANKSGIVING


December 3, 2024

Lais Da Silva, PhD, MS
Assistant Research Professor of Medicine
Division of Clinical Pharmacology
Indiana University School of Medicine

 

December 10, 2024

Jim Tisdale, PharmD
Professor, College of Pharmacy, Purdue University
Adjunct Professor of Medicine, Division of Clinical Pharmacology, Indiana University School of Medicine


December 17, 2024

Syed Zaidi, PharmD, PhD
Postdoctoral Fellow
Division of Clinical Pharmacology
Indiana University School of Medicine


December 24, 2024

NO SEMINAR - HAPPY HOLIDAYS

This calendar is subject to change.

January 3, 2022
NO SEMINAR - WINTER BREAK  


January 10, 2023
NO SEMINAR - WINTER BREAK


January 17, 2023
NO SEMINAR - WINTER BREAK


January 24, 2022
"Teamwork makes the dream work: Collaboration on an interesting patient case" Emma Tillman, PharmD, PhD
Associate Research Professor of Medicine
and
Mary Wermuth, MD
Assistant Professor of Clinical Emergency Care

  

January 31, 2023

"Opioid Literature Review and PBPK Lactation Model of Gabapentin"

Yaseen Abbasi, PhD
Postdoctoral Fellow

 

 

February 7, 2023
NO SEMINAR



February 14, 2023
SEMINAR POSTPONED (2/28/2023)

 

 

February 21, 2023

"Mechanisms and Clinical Implementations of Interplay Between Androgen Receptor and Its Splice Variants"

Bo Cao, PhD
T32 Postdoctoral Fellowship Candidate
Xavier University of Louisiana



February 28, 2023

"Development of SUMO1 Small Molecule Degraders as the First-in-Class Anticancer drugs through entrepreneurship"

Anita Bellail, PhD
Assistant Professor of Pathology & Laboratory Medicine

 

 

March 7, 2023

"Evaluation of cytochrome P450 inhibition by the synthetic cathinones butylone and MDPPP"

Ashley Springer
T32 Postdoctoral Fellowship Candidate
Manchester University



March 14, 2023
NO SEMINAR

 

 

March 21, 2023
NO SEMINAR - AMERICAN SOCIETY FOR CLINICAL PHARMACOLOGY & THERAPEUTICS (ASCPT)

 

 

March 28, 2023
NO SEMINAR - CANCELLED

 

 

April 4, 2023

"Prediction of Human Pharmacokinetics and Doses to Inform First in Human Studies"

Gary Mo, PhD
Director at Pfizer, Clinical Pharmacology Oncology
and
Maria Posada, PhD
Senior Director at Eli Lilly and Company

 

 

April 11, 2023
NO SEMINAR (POSTPONED 5/2/2023)

 

 

April 18, 2023

SEMINAR CANCELED 

 

April 25, 2023

"Pharmacokinetics of SHIP1 inhibitors in a mouse model of Alzheimer’s disease"

Murugesh Kandasamy, PhD
Postdoctoral Fellow

 

 

May 2, 2023

"Updates on implementing pharmacogenetic testing at IU"

Todd Skaar, PhD
Professor of Medicine

 

 


May 9, 2023

 "Pulling the Thread: Follow-up Research of a Putative mirSNP in Angiotensinogen"

Nick Powell, PharmD
Assistant Research Professor of Medicine
 

 


May 16, 2023
"Unintentional Adolescent Overdose: Recent Trends and Harm Reduction Approaches"

Lauren A. Bell, MD, MPH
Postdoctoral Fellow

 

 

 
May 23, 2023
 
"Predicting the Effect of Renal Function on Systemic Clearance: Is a Simple Scaling Method Sufficient?"

Darius Meiman, PharmD
Postdoctoral Fellow

 

 

May 30, 2023
NO SEMINAR - MEMORIAL DAY HOLIDAY

 

 

June 6, 2023

"The cell-type and region-specific chromatin landscape of the kidney in health and adaptive injury"

Debora Gisch, PhD
Postdoctoral Fellow

 

 

June 13, 2023

"Small Molecule PLCG2 Activators as a Therapeutic Strategy for the Treatment of Alzheimer’s Disease"

Brent Clayton, PhD
Associate Research Professor of Medicine

 

 

June 20, 2023

"The Development of PBPK Model for Dexmedetomidine in Pediatric Patients"

Aislinn O'Kane, PharmD
Postdoctoral Fellow

 

 

June 27, 2023
NO SEMINAR

 

 

July 4, 2023
NO SEMINAR - INDEPENDENCE DAY

 

 

July 11, 2023
NO SEMINAR

 

 

July 18, 2023
NO SEMINAR

 

 

July 25, 2023
NO SEMINAR

 

 

August 1, 2023

"PI3CK2A Kinase Inhibitors for Triple Negative Breast Cancer: Design, Synthesis, and Therapeutic Evaluation"

Chetna Jadala, PhD
Postdoctoral Fellow

 

 

August 8, 2023
SEMINAR CANCELLED

 

August 15, 2023
SEMINAR CANCELLED

 

 

August 22, 2023

"A Cellular and Molecular Atlas of the Kidney"

Michael Eadon, MD
Associate Professor of Medicine

 

 

August 29, 2023

"The Maternal Pediatric PRecision in Therapeutics (MPRINT) Hub"

Sara Quinney, PharmD, PhD
Professor of Obstetrics & Gynecology

 

 

September 5, 2023
NO SEMINAR - LABOR DAY

 

 
September 12, 2023

"Advancing Precision Medicine in Clinical Oncology"

Tyler Shugg, PharmD, PhD
Assistant Research Professor of Medicine

 


September 19, 2023

"Mitigating Immune-Mediated Inflammation in Hypertension"

Allison E. Norlander, PhD
Assistant Professor of Anatomy, Cell Biology & Physiology

 

 

September 26, 2023
NO SEMINAR

 

 

October 3, 2023

"Potent and Selective Small-Molecule Tool Compounds to Probe the Role of Lyn in Alzheimer's Disease"

Pathum Weerawarna, PhD
Assistant Research Professor of Medicine

 

 

October 10, 2023

"Drug-Gene-Nutraceutical Interactions of Cannabidiol and Tacrolimus"

Gerald So, PharmD
Postdoctoral Fellow

 

 

October 17, 2023

"Enoxaparin Pharmacokinetics and Dose Optimization in Neonates and Infants using Real World Data"

Michael M. Attah, PharmD (RPh), MS
PhD Candidate: Clinical Pharmaceutical Science

 

 

October 24, 2023

"Cell-Based Target Engagement Assays for Alzheimer’s Disease (AD) Drug Discovery"

Emily Mason, PhD
Postdoctoral Fellow

 

 

October 31, 2023

“Reducing the Risk of Drug-Induced QT Interval Lengthening: Population PK/PD Modeling”

Min Yue
Graduate Student
Purdue University College of Pharmacy

 

 

November 7, 2023
NO SEMINAR - AMERICAN CONFERENCE ON PHARMACOMETRICS

 

 

November 14, 2023
Elizabeth Rowe, PhD
Postdoctoral Fellow

 

 

November 21, 2023
NO SEMINAR - THANKSGIVING

 

 

November 28, 2023
Omar Aboshady, MD, MSc
Graduate Student

 

 

December 5, 2023
Timothy Richardson, PhD
Senior Research Professor of Medicine

 

 

December 12, 2023
James E. Tisdale, PharmD, FCCP, FAPhA, FNAP, FAHA, FACC
Professor, Department of Pharmacy Practice
Adjunct Professor, Indiana University School of Medicine

 

 

December 19, 2023
John T. Callaghan, MD, PhD
Associate Professor of Medicine

 

 

December 26, 2023
NO SEMINAR - WINTER BREAK

January 4, 2022
NO SEMINAR - WINTER BREAK  

January 11, 2022
NO SEMINAR 

January 18, 2022
Thomas D. Nolin, PharmD, PhD, FCCP, FCP, FASN
Associate Dean for Research and Sponsored Programs
Director, Small Molecule Biomarker Core
Associate Professor of Pharmacy and Therapeutics
University of Pittsburgh School of Pharmacy
“Pursuing Improved Drug Development and Use in CKD: Insights into Nonrenal and Extracorporeal Clearance”

 

January 25, 2022
Todd Skaar, PhD
Professor of Medicine
"Update on Pharmacogenomics discovery and implementation"

 

February 1, 2022
NO SEMINAR

 

February 8, 2022
NO SEMINAR

 

February 15, 2022
NO SEMINAR - CTSI M&S SYMPOSIUM

 

February 22, 2022
NO SEMINAR

 

March 1, 2022
NO SEMINAR

 

March 8, 2022
Ricardo Melo Ferreria, PhD
Postdoctoral Fellow
"Kidney Real Estate: The search for the best neighborhood"

 

March 15, 2022
NO SEMINAR - ASCPT/IUPUI SPRING BREAK

 

March 22, 2022
Elizabeth Rowe, PhD
Postdoctoral Fellow
"Pharmacogenomics and Antidepressant Prescribing Patterns in Advanced Cancer Patients"

 

March 29, 2022
Wilberforce Osei
Graduate Student
"Assess the feasibilityof using somatic WES data to call germline PGx genotypes"

 

April 5, 2022
Christopher Bartlett, PhD
Associate Professor of Pediatrics
College of Medicine
The Ohio State University
“EHR Data is Better Together: From Institutional Silos into Strengths”

 

April 12, 2022
Nick Powell, PharmD
Postdoctoral Fellow
“CYP2C19 is Downregulated in NAFLD”.

 

April 19, 2022
Cynthia Harris, PharmD
Principal Research Scientist, Medical Development, Immunology
Eli Lilly and Company
“Precision Guiding Dosing of Infliximab”

 

April 26, 2022
Debora Gisch, PhD
Postdoctoral Fellow
"DNA methylation in renal compartment"

 

May 3, 2022
Victoria Pratt, PhD, FACMG
VP Molecular Diagnostics Quality Assessments
Optum Genomics
Adjunct Professor, Medical and Molecular Genetics
Indiana University School of Medicine
"AMP’s Recommendations for Clinical TPMP/NUDT15 Allele Testing"

 

May 10, 2022
Nadia Bamfo, PharmD
Postdoctoral Fellow
"Clinical Study on Steady State PK of Dolutegravir/Rilpivirine (Fixed Dose Combination) in ESRD Patients Requiring Hemodialysis (HD)"

 

May 17, 2022
NO SEMINAR

 

May 24, 2022
Nick Miles, PharmD
Postdoctoral Fellow
"Using PBPK Modeling to investigate the Drug-Drug Interaction between Fluoxetine and Clopidogrel"

 

May 31, 2022
NO SEMINAR - WEEK OF MEMORIAL DAY HOLIDAY

 

June 7, 2022
Rebecca Silvola, PharmD
Postdoctoral Fellow
“PopPK Analysis to Estimate Gabapentin Exposure in Breastfed Neonates Immediately Following Cesarean Delivery”

 

June 14, 2022
NO SEMINAR

 

June 21, 2022
Paul Territo, PhD
Professor of Medicine
“Pharmacokinetic, Pharmacodynamic, and Transcriptomic Analysis of Chronic Levetiracetam Treatment in 5XFAD Mice: A MODEL-AD Preclinical Testing Core Study”

 

June 28, 2022
NO SEMINAR

 

July 5, 2022
NO SEMINAR - JULY 4TH HOLIDAY

 

July 12, 2022
David Haas, MD
Robert A. Munsick Professor of Obstetrics & Gynecology

"The PHI Hoosier Moms Cohort: opportunities for collaboration and analyses for all"

 

July 19, 2022
NO SEMINAR

 

July 26, 2022
Burcin Ekser, MD, PhD
Associate Professor of Surgery
Director, Transplant Research
Director, Transplant Immunology and Xenotransplantation Research Labs
Division of Transplant Surgery, Department of Surgery
Indiana University School of Medicine

"Advanced in Vitro 3D Human Liver Models"

 

August 2, 2022
Blessed Winston Arul Dhas, MD, MBBS
Assistant Research Professor of Medicine

"Population Pharmacokinetics of Opioids"

 

August 9, 2022
Catherine MT Sherwin, PhD, MPharm, DABCP, FCP, CPI
Professor & Vice Chair for Research
Director, Pediatric Clinical Pharmacology
Department of Pediatrics
Professor of Pharmacology & Toxicology
Wright State University Boonshoft School of Medicine
Dayton Children's Hospital

"Proof is in the pudding: the utilization pharmacokinetics and size variables for children"

 

August 16, 2022
Michael Eadon, MD
Associate Professor of Medicine

"Spatial transcriptomics and the kidney"

 

August 23, 2022
NO SEMINAR

 

August 30, 2022
QiPing Feng, PhD
Assistant Professor of Medicine
Clinical Pharmacology
Vanderbilt University Medical Center

Pleiotropic effects of lipids and lipid-lowering medications."

 

September 6, 2022
NO SEMINAR -  LABOR DAY

 

September 13, 2022
Chimnonso Onuoha, PharmD
Postdoctoral Fellow

"Physiologically Based Pharmacokinetics (PBPK) Modeling to Study Hops Compound 8-Prenylnarinenin (8-PN): Elucidating potential mechanisms underlying drug-hop interactions"

 

September 20, 2022
Sara Quinney, PhD
Associate Professor or Obstetrics & Gynecology

"The Importance of PBPK Model Validation and Reproducibility"

 

September 27, 2022
Emily Mason, PharmD
Postdoctoral Fellow

"Design & Implementation of Cell-Based Assays for Alzheimer's Disease (AD) Drug Discovery"

 

October 4, 2022
Darius Meiman, PharmD
Postdoctoral Fellow

"Physiologically Based Pharmacokinetic Model to Assess the Drug-Drug-Gene Interaction Potential of Belzutifan in Combination with Cyclin-Dependent Kinase 4/6 Inhibitors in Healthy Volunteers".

 

October 11, 2022
Rachael R. Schulte, MSCI, MD
Assistant Professor of Clinical Pediatrics
Pediatric Hematology and Oncology
Indiana University School of Medicine

 

October 18, 2022
Tyler Shugg, PharmD, PhD
Assistant Research Professor of Medicine

"Precision Medicine Approaches to Optimize Immune Checkpoint Inhibitor Therapy"

 

October 25, 2022
Lauren A. Bell, MD, MPH
Postdoctoral Fellow

"Denial and Self-Management: How Adolescents and Young Adults Initiate, Escalate, Problematize, and Contemplate Disclosure and Treatment of Opioid Use"

 

November 1, 2022
NO SEMINAR - Week of ACoP

 

November 8, 2022
Zeruesenay Desta, PhD
Professor of Medicine

"CYP2B6: from bench to clinic"

 

November 15, 2022
Tim Richardson, PhD
Senior Research Professor of Medicine

"Progress of the TREAD-AD Center"

 

November 22, 2022
NO SEMINAR - WEEK OF THANKSGIVING

 

November 29, 2022
Emma Tillman, PhD, PharmD
Associate Research Professor of Medicine

"Association of mental health adverse drug reactions with highly effective CFTR modulator therapy"

 

December 6, 2022
James Tisdale, PharmD
Adjunct Professor of Medicine

"Small-Conductance Calcium-Activated Potassium Current as a Possible Drug Target for Atrial Fibrillation" 

 

December 13, 2022
Shaoyou Chu, PhD, MD
Senior Research Professor of Medicine

“Cellular assays supporting TREAD-AD Center drug discovery projects targeting microglia"

 

December 20, 2022
NO SEMINAR - WINTER BREAK

 

December 27, 2022
NO SEMINAR - WINTER BREAK

January 5, 2021
NO SEMINAR  

 

January 12, 2021
Larissa Silva, PhD
Postdoctoral Fellow
"Maternal Betamethasone pharmacokinetics and Respiratory Distress Syndrome in neonates"

 

January 19, 2021
Paul Territo, PhD
Senior Research Professor
"MODEL-AD: Development of the Next Generation ofLate-Onset Alzheimer’s Disease (LOAD) Models"

 

January 26, 2021
Blessed Winston Arul Dhas, MD, MBBS
Postdoctoral Fellow
"PK modelling of Methadone in Children undergoing Major Surgery"

 

February 2, 2021
Tarun Mapder, PhD
Postdoctoral Fellow
"Variability in adaptive immune response and Remdesivir pharmacokinetics in population of SARS-CoV-2 infected within-host models"

 

February 9, 2021
NO SEMINAR - FELLOWS RETREAT

 

February 16, 2021
Peter Kissinger, PhD
Professor of Chemistry, Purdue Chairman and CEO, Bioanalytical Systems, Inc.
"Should we be overcoming the tyranny of averages with dosing by integrating modeling with measuring in individual patients?”

 

February 23, 2021
Lindsey Kirkpatrick, DO, PhD
Postdoctoral Fellow
"Current Challenges in Drug Quantitation from a Clinician’s View: Can Paper Spray Mass Spectrometry Fill the Gap?”

 

March 2, 2021
Yana Vorontsova, PharmD, MBA
Postdoctoral Fellow
"Development of a Natural Language Processing Machine to Identify Opioid Use Disorder in Electronic Health Records"

 

March 9, 2021
NO SEMINAR - ASCPT

 

March 16, 2021
NO SEMINAR; CANCELLED

 

March 23, 2021
NO SEMINAR - FOURTH YEAR COURSE

 

March 30, 2021
Elizabeth Rowe, PhD
Postdoctoral Fellow
"QT Interval Prolongation and Polypharmacy in Advanced Cancer Patients: Implications for Clinical Trial Eligibility"

 

April 6, 2021
Nadia Bamfo, PharmD
Postdoctoral Fellow
"PBPK models to predict stereo selective metabolism of bupropion and CYP2D6-mediated DDIs"

 

April 13, 2021
Nick Powell , PharmD
Postdoctoral Fellow
"Life-Threatening Docetaxel-Induced Pneumonitis in a Patient with Loss-of-Function Variants in CYP3A4, CYP3A5, and ABCC2: A Potential for Genetic Risk Scores"

 

April 20, 2021
Alexander B. Niculescu, III, MD, PhD
Professor of Psychiatry and Medical Neuroscience, IU School of Medicine
Director, INBRAIN and Laboratory of Neurophenomics
"Towards Precision Medicine in Psychiatry"

 

April 27, 2021
Vicky Pratt, PhD, FACMG
Professor of Clinical Medical & Molecular Genetics
"AMP’s Recommendations for CYP2D6 Allele Testing"

 

May 4, 2021
Marc Rosenman, MD
Associate Professor of Pediatrics, Northwestern University
"Retrospective EHR methods in support of PGX studies"

 

May 11, 2021
Chimnonso Onuoha, PharmD
Postdoctoral Fellow
"The utility of miRNA biomarkers in coronary artery disease"

 

May 18, 2021
NO SEMINAR - SIMCYP

 

May 25, 2021
Rebecca Silvola, PharmD
Postdoctoral Fellow
"PK and transfer of gabapentin during breastfeeding when used to reduce opioids after cesarean delivery"

 

June 1, 2021
Nick Miles, PharmD
Postdoctoral Fellow
"Modeling the Drug-Drug Interaction of Fluoxetine and Clopidogrel"

 

June 8, 2021
Shaoyou Chu, MD, PhD
Senior Research Professor
"Cellular assay development supporting AD drug discovery targeting microglia"

 

June 15, 2021
NO SEMINAR; CANCELLED

 

June 22, 2021
Reynold Ly, PhD
Postdoctoral Fellow
"Lessons and experiences learned from implementing Germline PGx Testing in the IU Precision Genomics Clinic"

 

June 29, 2021
NO SEMINAR

 

July 6, 2021
NO SEMINAR

 

July 13, 2021
Ricardo Melo Ferreira, PhD
Postdoctoral Fellow
"Spatial transcriptomics of kidney injury"

 

July 20, 2021
Takacs/Storey/Kuhn, Krishnan
Lilly IU School of Medicine/CTSI Research Partnership
"Lilly IU School of Medicine/CTSI Strategic Research Partnership - Understanding Autoimmune Disease Therapy through Transcriptome Analysis"

 

July 27, 2021
NO SEMINAR; CANCELLED

 

August 3, 2021
NO SEMINAR

 

August 10, 2021
Tyler Shugg, PhD, PharmD
Postdoctoral Fellow
"Ongoing Projects in Pharmacogenetics Discovery and Implementation"

 

August 17, 2021
Larissa Silva, PhD
Postdoctoral Fellow
"Modeling approaches for oral absorption: the APX3330 example"

 

August 24, 2021
David M. Haas, MD, MS
Robert A. Munsick Professor of Obstetrics & Gynecology
"Studying the impact of environmental pesticides on pregnancy outcomes- the Heartland Study"

 

August 31, 2021
Michael T. Eadon, MD, BA
Associate Professor of Medicine
"An Atlas of Healthy and Inured Kidney Cells"

 

September 7, 2021
Prashant Desai, PhD
Director, ADME Lilly Corporate Center
"Model-Informed Drug Discovery and Development"

 

September 14, 2021
NO SEMINAR

 

September 21, 2021
Young Jeong, PhD, PharmD
Professor, Purdue University, Department of Industrial and Physical Pharmacy
"Gut bacterial metabolites modulate drug efficacy and toxicity"

 

September 28, 2021
Sara Quinney, PhD
Associate Professor of Obstetrics & Gynecology
"Indiana University-Ohio State University Maternal and Pediatric Precision in Therapeutics Data and Model Knowledge Research Coordination Center (MPRINT DMKRCC)"

 

October 5, 2021
Emily Mason, PhD
Postdoctoral Fellow
"Design and Implementation of Cell-Based Assays for Alzheimer's Disease (AD) Drug Discovery"

 

October 12, 2021
Zeruesanay Desta, PhD
Professor of Medicine
"Mechanisms and Extent of Bupropion-CYP2D6 interaction"

 

October 19, 2021
NO SEMINAR

 

October 26, 2021
Tarun Mapder, PhD
Postdoctoral Fellow
"Multiscale Approaches in Modeling Disease and Therapeutics"

 

November 2, 2021
Timothy Richardson, PhD
Senior Research Professor of Medicine
“Targeting SHIP1 and PLCG2 and Immunomodulation of Alzheimers Disease. Targeting a Class II PI3K Kinase to Augment Immunotherapy in Cancer.”

 

November 9, 2021
John T. Callaghan, MD, PhD, MA
Associate Dean for VA Research
“MCAS, IMID,…Acronyms of Import?”

 

November 16, 2021

Brenda Roseberry
Division Manager, Scientific
Preclinical/Clinical—PK, Pharmacology, Pharmacometrics, Biomarkers
Carter Mackay
“CV Preparation For Applications and Interviews in the Pharmaceutical Industry”

 

November 23, 2021
NO SEMINAR - THANKSGIVING WEEK

 

November 30, 2021
Emma Tillman, PhD, PharmD
Associate Research Professor of Medicine
“Identifying the problem is essential to finding a solution: An approach to detecting and preventing adverse drug reactions (ADRs) in children”

 

December 7, 2021
James Tisdale, PharmD, FCCP, FAPhA, FNAP, FAHA, FACC
Professor, College of Pharmacy, Purdue University and Adjunct Professor, School of Medicine, Indiana University
“Sex Hormones, Ventricular Repolarization and Proarrhythmia”

 

December 14, 2021
Rolf Kreutz, MD
Associate Professor of Clinical Medicine
“Personalizing Antithrombotic Therapy in Interventional Cardiology: Finding the Right Balance”

 

December 21, 2021
NO SEMINAR - WINTER BREAK

 

December 28, 2021
NO SEMINAR - WINTER BREAK

January 7, 2020
No Seminar

 

January 14, 2020
No Seminar

 

January 21, 2020
No Seminar

 

January 28, 2020
No Seminar

 

February 4, 2020
No Seminar

 

February 11, 2020
Saugat Adhikari
PhD Candidate, College of Pharmacy, Purdue University
"Designing combination drug regimens to improve glioblastoma chemotherapy: A pharmacokinetic pharmacodynamic modeling approach"

 

February 18, 2020
No Seminar

 

February 25, 2020
Ryan S. Funk, PharmD, PhD
Assistant Professor of Pharmacy Practice, University of Kansas Medical Center
"A Clinical Pharmacologists Approach to the Identification of Molecular Biomarkers of Methotrexate Response in Juvenile Idiopathic Arthritis"

 

March 3, 2020
Nianjun Liu, PhD
Interim Department Co-Chair, Epidemiology and Biostatistics Professor, Indiana University
"Genetics of Warfarin Dose Response"

 

March 10, 2020
Yana Vorontsova, PharmD
Postdoctoral Fellow, Division of Clinical Pharmacology, IU School of Medicine
"Pharmacokinetics of Buccal vs Vaginal Misoprostol for Labor Induction at Term"

 

March 17, 2020
No Seminar - ASCPT

 

March 24, 2020
No Seminar - 4th Year Course

 

March 31, 2020
Natalie Lambert, PhD
Associate Professor of Medicine, Department of Medicine, IU School of Medicine; Affiliate, Regenstrief Institute; Investigator, Center for Computational Biology and Bioinformatics
CANCELED - COVID-19

 

April 7, 2020
Chandrali Bhattacharya
PhD Candidate, College of Pharmacy, Purdue University
CANCELED - COVID-19

 

April 14, 2020
Victoria Pratt, PhD
Professor of Clinical Medical & Molecular Genetics, Director of Pharmacogenomics and Molecular Genetics Laboratories, IU School of Medicine
"Establishing Pharmacogenetic Clinical Testing Panels"

 

April 21, 2020
No Seminar

 

April 28, 2020
Ashley E. Rawson, MD
Postdoctoral Fellow, Pediatric Clinical Pharmacology, IU School of Medicine
"Using Zebrafish to Identify Potential Genetic Targets in Kidney Infection"

 

May 5, 2020
Min Zhang, MD, PhD
Professor, Department of Statistics, Associate Director of Data Science, Purdue University Center for Cancer Research
No Seminar - will reschedule when we return on campus - POSTPONED - COVID-19

 

May 12, 2020
No Seminar

 

May 19, 2020
Shaoyou Chu, PhD
Senior Research Professor of Medicine, Division of Clinical Pharmacology, IU School of Medicine
"Cellular pharmacology aspect of antibody drug conjugate discovery"

 

May 26, 2020
No Seminar

 

June 2, 2020
Eric A. Benson, MD, PhD
Assistant Professor of Medicine, Division of Clinical Pharmacology, IU School of Medicine
"Blood Circulating Extracellular Kinetics from Assay Development to 3 Compartment Model"

 

June 9, 2020
Anh Duong, PharmD
Postdoctoral Fellow, Division of Clinical Pharmacology, IU School of Medicine
"Prediction of Voriconazole Drug-Gene and Drug-Drug-Gene Interaction Using a Physiologically Based Pharmacokinetic (PBPK) Model"

 

June 16, 2020
Maayan Leroy-Melamed, MD
Postdoctoral Fellow, Adolescent Medicine and Division of Clinical Pharmacology, IU Health & IU School of Medicine
"Provider Views on Sexual and Reproductive Health for Adolescent and Young Adults with Sickle Cell Disease"

 

June 23, 2020
Tom De Luca, PhD
Postdoctoral Fellow, Division of Clinical Pharmacology, IU School of Medicine
CANCELED

 

June 30, 2020
David M. Haas, MD
Robert A. Munsick Professor of Obstetrics & Gynecology, Department of Obstetrics & Gynecology, IU School of Medicine
"Cardiovascular Disease in Pregnancy: What does it mean for long-term health and how can research improve outcomes?"

 

July 7, 2020
No Seminar

 

July 14, 2020
J. Thomas Callaghan, MD, PhD, and Richard Bergstrom, PhD
"Clinical Studies Experimental Design’s and the Foibles of Research | Lessons from COVID-19 / SARS-CoV-2 Research"

 

July 21, 2020
No Seminar

 

July 28, 2020
Timothy I. Richardson, PhD
Senior Research Professor of Medicine, Division of Clinical Pharmacology, IU School of Medicine
"A Medicinal Chemist’s Perspective on Translational Research • Introduction to the IU School of Medicine-Purdue TREAT-AD Center • Defining Target Engagement at an Orphan Nuclear Receptor for the Treatment of Autoimmunity"

 

August 4, 2020
No Seminar

 

August 11, 2020
Michael T. Eadon, MD
Assistant Professor of Medicine, Division of Nephrology and Division of Clinical Pharmacology, IU School of Medicine
"Integration of single cell and spatial transcriptomics in the kidney"

 

August 18, 2020
No Seminar

 

August 25, 2020
No Seminar

 

September 1, 2020
No Seminar

 

September 8, 2020
Ebony Shah-Williams
PhD Candidate, Medical & Molecular Genetics, IU School of Medicine
"Diversity, Inclusion and Health /Identifying race specific genetic biomarkers of Taxane Induced Peripheral Neuropathy in African-American breast cancer patients"

 

September 15, 2020
Reynold Ly, PhD
Postdoctoral Fellow, Division of Clinical Pharmacology, IU School of Medicine
"Analytical Validation of a Computational Method, Aldy, for Pharmacogenomics Genotyping from Clinical Whole Exome Sequencing"

 

September 22, 2020
Robert E. Stratford, PhD
Associate Professor of Medicine, Director of the Disease and Therapeutic Response Modeling and Simulation Program, IU School of Medicine
"Application of Modeling and Simulation to provide insight to existing and new clinical research problems"

 

September 29, 2020
Sara K. Quinney, PharmD, PhD
Associate Professor, Department of Obstetrics & Gynecology; Associate Director, Disease and Therapeutic Response Modeling and Simulation Program; Center for Computational Biology and Bioinformatics, IU School of Medicine
"Translational approaches to understanding high-dimensional drug-drug interactions"

 

October 6, 2020
Zeruesenay Desta, PhD
Professor of Medicine, Division of Clinical Pharmacology, IU School of Medicine
"Genomic and drug-drug interaction mechanisms of inter-individual difference in drug disposition"

 

October 13, 2020
Tyler Shugg, PharmD, PhD
Postdoctoral Fellow, Division of Clinical Pharmacology, IU School of Medicine
"Clinical Potential of Repurposing Sequencing Data From a Precision Oncology Clinic to Support Multi-Disciplinary Precision Medicine"

 

October 20, 2020
Kimberly Collins, PhD
Assistant Scientist in Medicine, Division of Clinical Pharmacology, IU School of Medicine
"Genotype-guided dosing of hydralazine"

 

October 27, 2020
No Seminar

 

November 3, 2020
Emma M. Tillman, PharmD, PhD
Associate Research Professor of Medicine, Division of Clinical Pharmacology, IU School of Medicine
"Identifying the problem is essential to finding a solution:An approach to detecting and preventing adverse drug reactions (ADRs) in children"

 

November 10, 2020
Anthony Raviele, PharmD
Postdoctoral Fellow, Division of Clinical Pharmacology, IU School of Medicine
"In vitro characterization of bictegravir metabolism byUDP-glucuronosyltransferase and cytochrome P450 Enzymes"

 

November 17, 2020
Joseph Ipe, PhD
Assistant Scientist in Medicine, Division of Clinical Pharmacology, IU School of Medicine
"Spatial omics to determine tumor heterogeneity and drug penetration"

 

November 24, 2020
Brian Overholser, PharmD, FCCP
Associate Professor of Pharmacy Practice, Department of Pharmacy Practice, Purdue University
"Calcium/Calmodulin-Dependent Protein Kinase II (CaMKII) Control of Cardiac Repolarization: Potential Mechanism for Arrhythmias during Heart Failure"

 

December 1, 2020
James E. Tisdale, PharmD, BCPS, FCCP, FAPhA, FAHA
Professor, College of Pharmacy, Purdue University and Adjunct Professor, IU School of Medicine
"Assessing the Effects of Drugs on Early Versus Late Ventricular Repolarization"

 

December 8, 2020
Todd Skaar, PhD
Professor of Medicine, Division of Clinical Pharmacology, IU School of Medicine
"Multi-disciplinary aspects of the implementation of clinical pharmacogenetic testing"

 

December 15, 2020
Nick Powell, PharmD
Postdoctoral Fellow, Division of Clinical Pharmacology, IU School of Medicine
"Identification of miRNA-mRNA interactome in primary hepatocytes and mirSNP functional testing"

 

December 22, 2020
Ricardo Ferreira, PhD
Postdoctoral Fellow, Division of Clinical Pharmacology, IU School of Medicine
"Spatial transcriptomic signatures of the human kidney and murine models of kidney injury"

 

December 29, 2020
No Seminar