radiology and imaging sciences

Research

Since the first X-ray in 1895, radiology has become essential to health care. For over 75 years, the Department of Radiology and Imaging Sciences at Indiana University School of Medicine has been at the forefront, empathizing with patients, refining diagnoses and advancing preventative treatments. But before life-saving diagnoses are made, research innovations are crucial to elevate standards of care and enhance imaging technology. From breakthroughs in interventional radiology to pioneering discoveries in PSMA PET imaging, radiology remains a cornerstone of modern medicine. 

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1 of only 33
nationally recognized Alzheimer's disease centers
$25M+
total research funding for 2024
#1
radiology department among Big Ten schools, according to the Academy for Radiology & Biomedical Imaging Research
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Medical Imaging Research Institute

Under the leadership of Rohan Dharmakumar, MD, PhD, vice chair of research for the Department of Radiology and Imaging Sciences, we are introducing the next generation of imaging science research and innovation at IU School of Medicine through the establishment of the Medical Imaging Research Institute and its interdisciplinary research centers, including the Center for Neuroimaging and the Cardiovascular Imaging Research Center.

The institute also has expanded the Research Imaging Core across its three locations to provide researchers, learners and industry partners access to the latest imaging research technologies.

A male physician speaks with a female patient, explaining her MRI scan results.

Indiana Alzheimer's Disease Research Center

The Indiana Alzheimer’s Disease Research Center is a multidisciplinary research program deeply committed to the goals of the National Alzheimer’s Project Act (NAPA) to prevent and effectively treat Alzheimer’s disease (AD) and related dementias (ADRD) by 2035. The center supports innovative research on the causes, risk factors, and biological underpinnings of AD/ADRD, with particular emphasis on early detection, precision medicine, and biomarker discovery. Major activities include advanced neuroimaging, genetics, and fluid biomarker research, as well as educational programs for researchers and outreach to broadly represented communities.

Research Centers

The Medical Imaging Research Institute augments the visibility of emerging imaging research through its multidisciplinary research centers, including the Center for Neuroimaging and the Cardiovascular Imaging Research Center. Our research centers are bolstered by a robust Research Imaging Core that includes the latest imaging technologies that provide a rising testing ground for preclinical and translational research that will change the way we treat patients in the future. Each research center possesses their own discipline-specific instrumentation and computational power where scientists, clinicians and industry partners work to develop novel diagnostics, interventions and therapeutics through innovative science, engineering, medicine and artificial intelligence.

Cardiovascular Imaging Research Center

The Cardiovascular Imaging Research Center propels cardiovascular research and discovery forward through the design, development and deployment of advanced imaging tools and translational research. Investigators primarily focus their research on disease that impacts the heart muscle, including ischemic heart disease, that stems from reduced oxygen supply to the heart muscle. Researchers here aim to better understand the structural, compositional and functional changes to the heart at each stage of heart disease, utilizing advanced imaging technologies, including MRI, positron emission tomography (PET), biomedical engineering methods, molecular immunological analyses and informatics.

Center for Neuroimaging Research

The Center for Neuroimaging Research was founded with the goal of expanding understanding of the human brain in health and illness through clinical and translational brain imaging research. The center applies innovative imaging technologies to study brain structure and function to enhance diagnostic capabilities to enable personalized treatment options for neurological conditions. Researchers use artificial intelligence, machine learning and radiochemistry to drive new discoveries to enhance prevention, quality of life and treatments of neurological disorders.

Research stories
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Rapid blood test can detect heart attack patients at highest risk of in-hospital death

A rapid blood test can help detect a dangerous heart condition. 

Professional headshots of Rohan Dharmakumar, PhD and Keyur Vora, MD
Cardiovascular Medicine

Not all heart attacks are the same, more customized treatments needed to prevent heart failure

World-renowned researchers who attended the Krannert Biennial hosted by the Krannert Cardiovascular Research Center at Indiana University School of Medicine in May 2023, agree that what happens to the heart muscle after a heart attack is just as critical as to how clinicians treat heart attacks as they happen. They co-authored a State-of-the-Art Review article published today in JACC: Advances on reperfused myocardial infarction (MI), the chief theme of the two-day conference that took a deep dive into damage caused by heart attacks, that cause red blood vessels to rupture and leak into the myocardium. While one-year mortality after a heart attack has decreased over the past several decades, researchers note 30% of heart attack patients may still be diagnosed with heart failure after on year.

Photo of Jason Allen, M.D., Ph.D., Rohan Dharmakumar, Ph.D. and David Aronoff. M.D.
Internal News

Radiology and medicine: a collaborative partnership

This month marks the beginning of a new partnership for the Department of Radiology and Imaging Sciences and the Department of Medicine that will lead to improved collaboration to advance medical imaging and improve patient care, particularly in cardiovascular care.