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medical imaging research institute

Research Imaging Core

The Research Imaging Core provides imaging services for clinical trial, observational and preclinical studies. The core also provides radiochemistry support for molecular imaging. Currently, the core is equipped with state-of-the-art imaging systems, including 3T MRI scanners, PET-CT scanners, CT scanners, Bruker 9.4T preclinical PET-MRI scanner, a medical cyclotron and radiochemistry facilities. Highly skilled faculty and staff are available to assist with research study designs.

A male physician points to a neuro scan while a female physician observes,
+200
active studies
+$54 million
in grant funding
+15,000
imaging studies

Clinical Research Imaging

Learn how to pursue clinical research imaging through the Research Imaging Core.

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Preclinical Research Imaging

Explore preclinical imaging services.

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Services

Neuroimaging, cardiovascular imaging, musculoskeletal imaging, vasculature imaging and abdominal imaging. Charged by the hour with a 30-minute minimum. Contrast and other drugs charged separately.

Neuroimaging, cardiovascular imaging and whole-body imaging. Charged by the hour with a 15-minute minimum. Radiopharmaceuticals, contrast. Uptake time is charged separately.

F-18( FDG, FET NaF, Fallypride , FSPG, MFBG, FET),N-13 Ammonia, AV-45,, C-11 (acetate, Raclopride, PIB, PBR28, Palmitate/GSK GSK‐1482160, UCB‐J) [O‐15]Water, Ga-PSMA-11. Please contact Michael L. Schulte, PhD for new radiotracer development.

 Research Imaging Core at Goodman Hall

 Description (Rates are hourly unless noted) Internal Rate   Comments
 3T MRI  $551  30 minute min
 PET/CT  $1271  30 minute min
 CT  $1271  15 minute min
 Tracer Uptake  $50  Flat fee
 Secretin 10ml  $1057.46  Flat fee
 Multihance 20ml  $154.95  Flat fee
 Gadavist 15ml  $45  Flat fee
 Study-Supplied Dose Handling  $65  Flat fee
 Research Imaging Technologist Time (PET/MR)  $120  Hourly

 


Radiopharmaceuticals

Description Internal Rate Comments
[F-18]FDG up to 15 mCi $125 Human
[F-18]FDG 20 mCi $177 Human
[F-18]NaF $159 Human
[N-13]Ammonia $200 Human
AV45 $3,029 Human
C-11 Acetate $1,198 Human
[C-11]/[F-18] Complex [C11](raclopride, PiB, PBR28, palmitate, GSK, GSK-1482160, UCB-J); [F18](FET, Fluorocholine, FSPG, F-AraG, Fallypride) $2,313 Human
[F-18] Batch Production (FSPG, MFBG, FET) $2,792 Human
F-18 FET Single Dose $1,457 Human
[O-15]Water $601 Human
Pentixafor $3,376 Human
PIB for DIAN-TU (IND) $2,422 Human
Gallium-PSMA-11 ILLUCCIX $6,792 Human
ILLUCCIX (Faculty Inititated) $1,857 Human
68Ga-PSMA - R01 $1,691 Human
68Ga-PSMA-11 $3,069 All other PSMA's
Ga-68 Chloride Radiochemical $1,016 Human
FAPI-46 $3,107 Human
11C-CO2 Blood Metabolite Assay $461 Other services
Faculty-initiated ILLUCCIX $1,857 Human
Research Cyclotron Beam Time (per hr, w/o production disruption) $125 Other services
Research IND Annual Maintenance Charge $12,344 Other services
Radiochemistry Development Fee $786 Other services
Courier Transport for Radioactive Packages $150 Other services

 

Office for Research Imaging

Description Internal Rate Comment
Annual Maintenance $245 Human studies only
Data Analysis $109 Staff
Data Analysis $130 Faculty
Data Transfer (sFTP,CD,Upload) $35 Internal rate only
Dosimetry $200 Flat fee
RECIST Tumor Measurements $185 Internal rate only
MRI Safety Reads $100 Internal rate only
PET-CT Safety Reads $100 Internal rate only

 

Preclinical Imaging Core - Research II Building

Description Internal Rate Comment
3T MRI $551 Full core staff support
Freemax $551 Full core staff support

 

Roberts Translational Imaging Facility - Neurosciences Research Building

Description Internal Rate Comment
9.4T PET/MR $317 With Core Staff Support
9.4T PET/MR $231 Without Core Staff Support

 

Other Preclinical Services

Description Internal Rate Comment
Animal Handling $50 Hourly
Data Analysis/Transfer - Staff $109 Hourly
Data Analysis/Transfer - Faculty $130 Hourly

 

Radiopharmaceuticals - Preclinical

Description Internal Rate Comment
[F-18]FDG up to 15 mCi $125 Non-human
[F-18]FDG 20 mCi $177 Non-human
[F-18]NaF $159 Non-human
[N-13]Ammonia $200 Non-human
AV45 $3,029 Non-human
Cu64~ (50 mcI) $1,687 Non-human
Cu64 (80 mCi) $2,527 Non-human
[Cu64]Cu-PTSM/synthesis $758 Non-human
Cu-64 Antibody Supplies $350
P16-093 Supplies $227
[C-11]Acetate $781 Non-human
[C-11]/[F-18] Complex [C11](raclopride, PiB, PBR28, palmitate, GSK, GSK-1482160, UCB-J); [F18](FET, Fluorocholine, FSPG, F-AraG, Fallypride) $1,577 Non-human
[F-18] Batch Production FCH, F-AraG, FET $1,919 Non-human
[O-15]Water $354 Non-human

Scheduling of all research is to be made in advance with core personnel for the equipment being scheduled. Specific scheduling instructions will be provided after studies have been registered with the Office of Research Imaging (ORI).  All users will be billed for the time scheduled OR for the time actually used, whichever is greater.

Cancellation and No Shows: Cancellation of scheduled scanner time must be two business days prior to the scheduled time or it will be considered a “no show” and billed at the full scan rate. If a radiopharmaceutical or other study drug is wasted due to a cancellation or no show the study will be charged for it. Late cancellations where the appointment slot gets filled will not be charged.

Images are stored in radiology’s long-term storage server. Study teams must specify if images are to be sent to a study specific server or outside destination.

Data should be removed from the scanner(s) as soon as possible after the examination. The imaging technologist has the right to remove all data older than one week. Data is the responsibility of the user (Principal Investigator). The Research Imaging Core may be contracted to archive data to specific locations for investigators; however, maintenance of the data is still the responsibility of the user. 

Depends on the availability of staff and upon request.

In the form of research collaboration.

In the form of research collaboration.

In the form of research collaboration.

Policies

Per CTSI policy, all imaging-related research work performed by the Research Imaging Core should be acknowledged in all ensuing publications. Fees paid for services provided by the core should not negate the qualification of co-authorship for the core scientists. These acknowledgements and achievements are important for the existence of the core facility. Given that many advanced imaging techniques and validated procedures require in-depth intellectual involvement by the core’s scientists (examples listed below), it is expected that this acknowledgement will be in the form of co-authorship according to the guidelines for authorship recommended by the International Committee of Medical Journal Editors. Research Imaging Core scientists performing one or more of the following tasks meet the criteria for authorship:
  • Literature review and providing assistance in selecting/conceiving the experiments appropriate for the study goals
  • Experimental design
  • Imaging sequence development/optimization
  • Data analysis and interpretation of data, or both
  • Preparation of pertinent sections (e.g., methods) or figures for the manuscript and revisions to address reviewer concerns/questions
All contributions that do not meet the criteria for authorship should be listed in the acknowledgments section. Examples of the tasks requiring an appropriate mention in the acknowledgment section are:
  • Mere collection of image data using PI-provided protocols that require no further optimization and/or trouble-shooting.
  • Mere collection of image study data without any data analyses or interpretation by the core scientists.
  • Initial consultation. 
  • Assistance in image data transfer or storage.
  • Clinical safety read for incidental findings

Please acknowledge the Research Imaging Core's help in a format similar to the one suggested below for publications and grant applications:

“… imaging was performed at the MIRI Research Imaging Core, which was established and supported by the Department of Radiology and Imaging Sciences.” 

Data obtained using facility equipment should include an acknowledgment of Indiana Institute for Biomedical Imaging Sciences.

Text descriptions of the facility where equipment was used is available for researchers wishing to describe grant applications. The institute can provide letters of consultation or collaboration, as needed. It is requested that users of equipment supply the institute with an updated list every six months of publications and grant applications that referencing institute facilities.

Data generated by the institute is kept on a secure server with access to core personnel only.

If a resolution cannot be reached at the director level, the issue will be taken to an advisory committee for discussion and resolution.

If recovery of payment becomes an issue, business managers will contact the customer and/ or their department to collect charges owed. If there is a dispute in charges, the conflict resolution policy above will be followed.

Studies or services will be on a first-come, first-serve basis. In the event that there is a back-log of studies or conflict in scheduling, services will be prioritized based on the following guidelines:

  • Extramural Grant Funded Research
  • Intramural and/or Industry Funded Research
  • Standard of Care Diagnostic Scans Unrelated to Research
  • Funded Pilot or Development Projects
  • Unfunded Pilot or Development Projects

Facilities

 

 

Goodman Hall and IU Health Neuroscience Center

IU Health Neuroscience Center

355 W. 16th St., Indianapolis, IN 46202

Research II (R2) Building

R2 Building

980 W. Walnut St., Indianapolis, IN 46202

Leadership

7079-Wu, Yu-Chien

Yu-Chien Wu, MD, PhD

Professor of Radiology & Imaging Sciences

Scientific Director

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Jason Shine, MBA, CCRP

Director, Research Operations

Contact Jason